BDB744471

CD24 Rat anti-Mouse, BUV395, Clone: M1/69, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB744471-Each-of-1 In Stock ₹ 34,224.00

BDB744471 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD24

Clone

M1/69

Conjugate

Brilliant Ultraviolet 395

Gene Alias

CD24a, HSA, Heat Stable Antigen, Ly-52, Nectadrin, R13-Ag

Immunogen

C57BL/10 Mouse Splenic T Lymphocytes

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2b κ

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Description

  • The M1/69 monoclonal antibody specifically binds to CD24 (Heat-Stable Antigen, HSA or HsAg), a variably glycosylated, glycosyl-phosphatidylinositol-anchored membrane protein expressed on erythrocytes, granulocytes, monocytes, lymphocytes, and neurons
  • Hematopoietic stem cells of the embryonic yolk sac and fetal liver express CD24
  • Levels of expression of CD24 vary during differentiation of the T and B cell lineages
  • In the bone marrow, hematopoietic progenitors acquire CD24 expression upon commitment to the B-lymphocyte lineage
  • Immature B cells in the bone marrow express low CD24 levels whereas peripheral B lymphocytes express intermediate to high levels of CD24
  • The level of CD24 expression has been reported to rise upon activation of splenic B cells with LPS, but not with CD154 (CD40 Ligand)
  • The majority of thymocytes express high levels of CD24, while most mature thymic and peripheral T lymphocytes do not express CD24
  • In contrast, TCR-bearing thymocytes which emigrate to the spleen are CD24+
  • Dendritic cells of the thymus, spleen, liver, and epidermal Langerhans cells have also been reported to express CD24
  • CD24 is not expressed by NK cells
  • CD24 is involved in the costimulation of CD4+ T cells by B cells, it is a co-inducer of in vitro thymocyte maturation, and it is a ligand of CD62P (P-selectin)
  • While the monoclonal antibodies 30-F1, M1/69, and J11d all react with CD24, they show subtle differences in the level of staining of different lymphocyte populations
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
  • BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
  • With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
  • This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB744471

--


Antigen:
CD24

Clone:
M1/69

Conjugate:
Brilliant Ultraviolet 395

Gene Alias:
CD24a, HSA, Heat Stable Antigen, Ly-52, Nectadrin, R13-Ag

Immunogen:
C57BL/10 Mouse Splenic T Lymphocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Img

BD Biosciences

BDB744473

--


Antigen:
Vδ 6.3/2 TCR

Clone:
8F4H7B7

Conjugate:
Brilliant Violet 510

Gene Alias:
V delta 6.3/2 TCR, TCR Vδ 6.3/2, TCR Vδ6.3/2, TCR Vd6.3/2

Immunogen:
1E6.11.D7, a C57BL/6 mouse Vγ1.1Vδ6.3 TCR-bearing IEL/T-cell hybridoma

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Armenian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2 κ

Img

BD Biosciences

BDB744474

--


Antigen:
Vδ 6.3/2 TCR

Clone:
8F4H7B7

Conjugate:
Brilliant Violet 605

Gene Alias:
V delta 6.3/2 TCR, TCR Vδ 6.3/2, TCR Vδ6.3/2, TCR Vd6.3/2

Immunogen:
1E6.11.D7, a C57BL/6 mouse Vγ1.1Vδ6.3 TCR-bearing IEL/T-cell hybridoma

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Armenian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2 κ

Img

BD Biosciences

BDB744477

--


Antigen:
Vδ 6.3/2 TCR

Clone:
8F4H7B7

Conjugate:
Brilliant Violet 786

Gene Alias:
V delta 6.3/2 TCR, TCR Vδ 6.3/2, TCR Vδ6.3/2, TCR Vd6.3/2

Immunogen:
1E6.11.D7, a C57BL/6 mouse Vγ1.1Vδ6.3 TCR-bearing IEL/T-cell hybridoma

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Armenian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2 κ