CBL1337I

MilliporeSigma™ PECAM-1, Rat, Unlabeled, Clone: 390,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 CBL1337I-Each-of-1 In Stock ₹ 37,453.03

CBL1337I - Each of 1

₹ 37,453.03

In Stock

Quantity

1

Base Price: ₹ 37,453.03

GST (18%): ₹ 6,741.545

Total Price: ₹ 44,194.575

Antigen

PECAM-1

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rat IgG2a in PBS without azide.

Gene Accession No.

Q08481

Immunogen

Mouse leukocyte cell line 32D.

Quantity

100 μL

Research Discipline

Cell Structure

Gene ID (Entrez)

NP_032842

Target Species

Mouse

Form

Purified

Applications

Immunofluorescence, Immunoprecipitation, Neutralization

Clone

390

Conjugate

Unconjugated

Gene

Pecam1, Pecam, Pecam-1

Host Species

Rat

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 390 immunoprecipitated the characteristic 120-130 kDa protein from L-cells transfected with muPECAM-1∆12,15 and selectively stained murine vessels in acetone-fixed tissue sections (Baldwin, H.S., et al. (1994). Development. 120(9):2539-2553).

Content And Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype

IgG2a κ

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Description

  • Platelet endothelial cell adhesion molecule (UniProt Q08481; also known as CD31, PECAM-1) is encoded by the Pecam1 (also known as Pecam, Pecam-1) gene (Gene ID 18613) in murine species
  • PECAM-1 (CD31) is a 130-kD cell adhesion molecule that is expressed at the junctions of all continuous endothelia, as well as most bone marrow-derived hematopoietic cells, including platelets, monocytes, granulocytes and some lymphocytes
  • The human PECAM1 and murine Pecam1 genes both produce multiple spliced isoforms with varying lengths in cytoplasmic domain, with the isoform Long being the major form expressed in human tissues and endothelial cells (ECs), and isoform delta 14-15 being the predominantly expressed murine form
  • PECAM-1 plays an import role in maintaining vascular integrity and function by mediating ECs interactions with pericytes and smooth muscle cells (SMCs)
  • PECAM-1 is initially produced with a signal peptide (human a.a
  • 1-27, murine a.a
  • 1-17) sequence, the removal of which yields the mature protein with a large extracellular region (human a.a
  • 28-601, mouse a.a
  • 18-590) composed of six C2-type Ig-like domains, followed by a transmembrane seqment (human a.a
  • 602-620, mouse a.a
  • 591-609) and a cytoplasmic tail (human a.a
  • 621-738, mouse a.a
  • 610-727) that plays an essential role in PECAM-1-mediated cellular signaling.

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MilliporeSigma™

CBL1337I

--


Antigen:
PECAM-1

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rat IgG2a in PBS without azide.

Gene Accession No.:
Q08481

Immunogen:
Mouse leukocyte cell line 32D.

Quantity:
100 μL

Research Discipline:
Cell Structure

Gene ID (Entrez):
NP_032842

Target Species:
Mouse

Form:
Purified

Applications:
Immunofluorescence, Immunoprecipitation, Neutralization

Clone:
390

Conjugate:
Unconjugated

Gene:
Pecam1, Pecam, Pecam-1

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 390 immunoprecipitated the characteristic 120-130 kDa protein from L-cells transfected with muPECAM-1∆12,15 and selectively stained murine vessels in acetone-fixed tissue sections (Baldwin, H.S., et al. (1994). Development. 120(9):2539-2553).

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG2a κ

Img

MilliporeSigma

CBL1337MI

--


Antigen:
PECAM-1

Classification:
Monoclonal

Concentration:
__

Formulation:
Protein A Purified mouse immunoglobulin in 100mM borate buffered saline, pH 8.0, containing no preservative.

Gene Accession No.:
NM_000442.3

Immunogen:
Mouse leukocyte cell line 32D

Quantity:
500 μg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Mouse

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Clone:
390

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rat

Purification Method:
Protein A purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Isotype:
IgG2a κ

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MilliporeSigma

CBL1345MI

--


Antigen:
Integrin α2

Classification:
Monoclonal

Concentration:
__

Formulation:
The affinity chromatography purified monoclonal is presented in phosphate buffered saline, pH 7.2, containing 0.09% sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Gene Accession No.:
NM_002203.3

Immunogen:
__

Quantity:
500 μg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Mouse

Form:
Purified

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation

Clone:
HMalpha2

Conjugate:
Unconjugated

Gene:
__

Host Species:
Armenian Hamster

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for up to 12 months.

Isotype:
IgG

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CBL1346Z-I

clone RMV-7, from rat...


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__