IM09L100UG
MilliporeSigma™ anti-MMP-9 Clone: 6-6B,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | IM09L100UG-Each-of-1 | In Stock | ₹ 44,393.20 |
IM09L100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,393.20
GST (18%): ₹ 7,990.776
Total Price: ₹ 52,383.976
Antigen
MMP-9
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Immunoprecipitation, Neutralization
Clone
6-6B
Formulation
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen
MMP-9 from conditioned medium of PMA-stimulated HT-1080 human fibrosarcoma cells
Regulatory Status
RUO
Test Specificity
Recognizes the ∽92kDa latent and the ∽83kDa active forms of MMP-9 under non-reducing conditions, but only the latent form under reducing conditions. Inhibits the enzymatic activity of MMP-9.
Content And Storage
2°C to 8°C
Isotype
IgG1
Related Products
Description
- Specifically detects MMP-9 Clone: 6-6B in Human samples, and it is validated for Immunoprecipitation, Neutralization Matrix metalloproteinases (MMP's) are a family of enzymes that are responsible for the degradation of extracellular matrix components such as collagen, laminin and proteoglycans
- In addition to sequence homology, all MMP's share the following characteristics: the catalytic mechanism is dependent upon a zinc ion at the active center, they cleave one or more extracellular matrix components, they are secreted as zymogens which are activated by removal of an ∽10kDa segment from the N terminus and they are inhibited by tissue inhibitor of metalloproteinases (TIMP)
- These enzymes are involved in normal physiological processes such as embryogenesis and tissue remodeling and may play an important role in arthritis, periodontitis, and metastasis
- MMP-9 (Gelatinase B, 92kDa gelatinase/type IV collagenase) is secreted as a 92kDa zymogen which is proteolytically processed to the 83kDa active form; a 68kDa has also been detected
- MMP-9, along with its most closely related member of the MMP family, MMP-2, show substrate specificity toward type IV and V collagens, gelatin and elastin
- Numerous studies have shown a correlation between collagenase expression and metastatic potential
- Elevated levels of MMP-9 in plasma suggest that it may be a useful marker for the diagnosis or prognosis of cancer in general.
Compare Similar Items
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Antigen: MMP-9
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoprecipitation, Neutralization
Clone: 6-6B
Formulation: Lyophilized from a volatile buffer, 100μg BSA.
Immunogen: MMP-9 from conditioned medium of PMA-stimulated HT-1080 human fibrosarcoma cells
Regulatory Status: RUO
Test Specificity: Recognizes the ∽92kDa latent and the ∽83kDa active forms of MMP-9 under non-reducing conditions, but only the latent form under reducing conditions. Inhibits the enzymatic activity of MMP-9.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
MMP-9
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoprecipitation, Neutralization
Clone:
6-6B
Formulation:
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen:
MMP-9 from conditioned medium of PMA-stimulated HT-1080 human fibrosarcoma cells
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽92kDa latent and the ∽83kDa active forms of MMP-9 under non-reducing conditions, but only the latent form under reducing conditions. Inhibits the enzymatic activity of MMP-9.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: Matriptase/MT-SP1
Classification: Polyclonal
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoprecipitation
Clone: __
Formulation: In Tris-citrate/phosphate buffer, pH 7.0-8.0.
Immunogen: a synthetic peptide corresponding to amino acids near the C-terminus of human matriptase
Regulatory Status: RUO
Test Specificity: Recognizes the ∽75kDa matriptase protein in MCF-7 cells.
Content And Storage: 2°C to 8°C
Isotype: IgG
Antigen:
Matriptase/MT-SP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoprecipitation
Clone:
__
Formulation:
In Tris-citrate/phosphate buffer, pH 7.0-8.0.
Immunogen:
a synthetic peptide corresponding to amino acids near the C-terminus of human matriptase
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽75kDa matriptase protein in MCF-7 cells.
Content And Storage:
2°C to 8°C
Isotype:
IgG
Antigen: PAI-1
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Immunoprecipitation, Neutralization
Clone: 2
Formulation: Lyophilized from a volatile buffer, 100μg BSA.
Immunogen: partially purified PAI-1 from conditioned medium of dexamethasone-treated HT1080 human cells
Regulatory Status: RUO
Test Specificity: Recognizes both active and latent forms of the ∽50kDa PAI-1 protein in conditioned media from dexamethasone-treated HT-1080 cells. Sold under license of U.S. Patent 5,422,245.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
PAI-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Immunoprecipitation, Neutralization
Clone:
2
Formulation:
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen:
partially purified PAI-1 from conditioned medium of dexamethasone-treated HT1080 human cells
Regulatory Status:
RUO
Test Specificity:
Recognizes both active and latent forms of the ∽50kDa PAI-1 protein in conditioned media from dexamethasone-treated HT-1080 cells. Sold under license of U.S. Patent 5,422,245.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: MMP-2
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Rat
Form: Purified
Applications: Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 42-5D11
Formulation: In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0
Immunogen: a synthetic peptide (VTPRDKPMGPLLVATF) corresponding to amino acids 468-483 of human MMP-2
Regulatory Status: RUO
Test Specificity: Recognizes the ∽72kDa latent and the ∽66kDa active forms of the MMP-2.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
MMP-2
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Rat
Form:
Purified
Applications:
Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
42-5D11
Formulation:
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0
Immunogen:
a synthetic peptide (VTPRDKPMGPLLVATF) corresponding to amino acids 468-483 of human MMP-2
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽72kDa latent and the ∽66kDa active forms of the MMP-2.
Content And Storage:
−20°C
Isotype:
IgG1