MABC534MI
MilliporeSigma™ Mouse anti-TPM3, Clone: TC22-4,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC534MI-Each-of-1 | In Stock | ₹ 38,673.12 |
MABC534MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,673.12
GST (18%): ₹ 6,961.162
Total Price: ₹ 45,634.282
Antigen
TPM3
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
TPM3
Immunogen
Recombinant human TC22 and boosts with TC22-specific C-terminal peptide.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_000357
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone
TC22-4
Gene Accession No.
P06753-4
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects TPM3 clone: TC22-4 in Human samples, and it is validated for ELISA, Flow Cytometry, Immunohistochemistry, Western Blotting Tropomyosins are dimmers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins
- The human TPM3 gene (Gene ID 7170; also known as TM3, TM5, TRK, CFTD, NEM1, TM-5, TM30, CAPM1, TM30nm, TPMsk3, hscp30, HEL-189, HEL-S-82p, OK/SW-cl.5) encodes seven tropomyosin alpha-3 chain isoforms (UniProt P06753; also known as Tropomyosin-3) as a result of alternative splicing
- Spliced variants 1, 2, 4, and 5 are also known as the skeletal muscle, TM30nm, TC22, and hTM5 isoform, respectively
- The TC22 and the hTM5 variants are identical in sequence other than the 25 amino acids at their C-terminal end
- TC22 is expressed in 100% of colorectal carcinomas, but is not expressed in normal colon epithelial cells
- The anticarcinogenic potency of sulfasalazine (SASP) and its active metabolite 5-aminosalicylate (5-ASA, mesalamine) in protecting ulcerative colitis (UC) patients from developing colorectal cancer is directly linked to their efficacy in reducing cellular expression of TC22
- Likewise, siRNA-mediated TC22 downregulation is shown to significantly alter several critical carcinogenic pathways in the human colon adenocarcinoma LS180 cells.
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Antigen: TPM3
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: TPM3
Immunogen: Recombinant human TC22 and boosts with TC22-specific C-terminal peptide.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_000357
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone: TC22-4
Gene Accession No.: P06753-4
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
TPM3
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
TPM3
Immunogen:
Recombinant human TC22 and boosts with TC22-specific C-terminal peptide.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_000357
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone:
TC22-4
Gene Accession No.:
P06753-4
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: BIRC2/IAP-2
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Birc2, Birc3, lap2
Immunogen: Linear peptide corresponding to the BIR 2 repeat region of mouse BIRC2/IAP-2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Applications: Western Blot
Clone: 1E1-1-10
Gene Accession No.: NP_031491
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
BIRC2/IAP-2
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Birc2, Birc3, lap2
Immunogen:
Linear peptide corresponding to the BIR 2 repeat region of mouse BIRC2/IAP-2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
1E1-1-10
Gene Accession No.:
NP_031491
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: Vasohibin-2
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives .
Gene Symbols: VASH2, VASHL
Immunogen: KLH-conjugated linear peptide corresponding to human Vasohibin 2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Western Blot
Clone: 5E3
Gene Accession No.: NP_001129946
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
Vasohibin-2
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives .
Gene Symbols:
VASH2, VASHL
Immunogen:
KLH-conjugated linear peptide corresponding to human Vasohibin 2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Western Blot
Clone:
5E3
Gene Accession No.:
NP_001129946
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: Vasohibin-1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols: VASH1, KIAA1036, VASH
Immunogen: KLH-conjugated linear peptide corresponding to Human Vasohibin-1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 4E12
Gene Accession No.: NP_055724
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Vasohibin-1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols:
VASH1, KIAA1036, VASH
Immunogen:
KLH-conjugated linear peptide corresponding to Human Vasohibin-1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
4E12
Gene Accession No.:
NP_055724
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified