MABD148MI
MilliporeSigma™ Lgr5 (GPR49), Mouse, Unlabeled, Clone: 5G10.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABD148MI-Each-of-1 | In Stock | ₹ 36,363.00 |
MABD148MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,363.00
GST (18%): ₹ 6,545.34
Total Price: ₹ 42,908.34
Antigen
Lgr5 (GPR49)
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
O75473
Immunogen
GST-tagged recombinant human Lgr5/GPR49 fragment corresponding to leucine-rich repeats (LRRs) 7-11 within the N-terminal extracellular domain.
Quantity
100 μg
Research Discipline
Stem Cell Research
Gene ID (Entrez)
NP_003658
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
5G10.1
Conjugate
Unconjugated
Gene
LGR5, GPR49, GPR67, GRP49, HG38
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 5G10.1 targets an epitope within human Lgr5 (GPR49) N-terminal extracellular region comprised of leucine-rich repeats (LRRs) 7-11. Reactivity toward spliced isoform 2 that lacks part of the LLRs 9&10 sequence is possible, but has not been confirmed.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2b κ
Related Products
Description
- Leucine-rich repeat-containing G-protein coupled receptor 5 (UniProt O75473; also known as G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, Orphan G protein-coupled receptor HG38) is encoded by the LGR5 (also known as GPR49, GPR67, GRP49, HG38) gene (Gene ID 8549) in human
- Lgr5 is a 7-transmembrane protein related to the receptors for the follicle stimulating hormone (FSH), the luteinizing hormone (LH), and the thyroid-stimulating hormone (TSH)
- Lgr5 is a Wnt signaling pathway targeted gene expressed in proliferative stem cells in various tissues, including small intestine, colon, stomach, and the hair follicle
- The R-spondin (RSPO) family of secreted Wnt signaling agonists are known to bind Lgr5 and the related Lgr4 and Lgr6, and RSPO1 depends on its association wth Lgr4, Lgr5, or Lgr6 for its Wnt signaling enhancing effect
- Human Lgr5 is synthesized with a propeptide sequence (a.a
- 1-21), the removal of which yields the mature 7-transmembrane (a.a
- 562-582 , 594-614, 639-659, 683-703, 723-743, 768-788, 803-823) G-protein-coupled receptor (GPCR), having its N-terminal end (a.a
- 22-561) at the extracellular side and its C-terminal end (a.a
- 824-907) at the cytoplasmic side
- The N-terminal extracellular region contains a leucine-rich repeat (LRR) N-terminal (LRRNT) domain (a.a
- 25-66), followed by 16 LRRs (LRR 1 through LLR 16; a.a
- 67-446).
Compare Similar Items
Show Difference
Antigen: Lgr5 (GPR49)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: O75473
Immunogen: GST-tagged recombinant human Lgr5/GPR49 fragment corresponding to leucine-rich repeats (LRRs) 7-11 within the N-terminal extracellular domain.
Quantity: 100 μg
Research Discipline: Stem Cell Research
Gene ID (Entrez): NP_003658
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 5G10.1
Conjugate: Unconjugated
Gene: LGR5, GPR49, GPR67, GRP49, HG38
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 5G10.1 targets an epitope within human Lgr5 (GPR49) N-terminal extracellular region comprised of leucine-rich repeats (LRRs) 7-11. Reactivity toward spliced isoform 2 that lacks part of the LLRs 9&10 sequence is possible, but has not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Lgr5 (GPR49)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
O75473
Immunogen:
GST-tagged recombinant human Lgr5/GPR49 fragment corresponding to leucine-rich repeats (LRRs) 7-11 within the N-terminal extracellular domain.
Quantity:
100 μg
Research Discipline:
Stem Cell Research
Gene ID (Entrez):
NP_003658
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
5G10.1
Conjugate:
Unconjugated
Gene:
LGR5, GPR49, GPR67, GRP49, HG38
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 5G10.1 targets an epitope within human Lgr5 (GPR49) N-terminal extracellular region comprised of leucine-rich repeats (LRRs) 7-11. Reactivity toward spliced isoform 2 that lacks part of the LLRs 9&10 sequence is possible, but has not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: podocalyxin associated keratan sulfate
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_001018121
Immunogen: Whole Human iPS cells (Tic cell line).
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Western Blot
Clone: R-10G
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Antigen:
podocalyxin associated keratan sulfate
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_001018121
Immunogen:
Whole Human iPS cells (Tic cell line).
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Western Blot
Clone:
R-10G
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Antigen: GATA1
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.: __
Immunogen: Purified recombinant fragment of human GATA1 expressed in E. Coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Ascites
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 4F5
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG2b
Antigen:
GATA1
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.:
__
Immunogen:
Purified recombinant fragment of human GATA1 expressed in E. Coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Ascites
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
4F5
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG2b
Antigen: WNT1
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.: __
Immunogen: Purified recombinant fragment of human WNT1 expressed in E. Coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse
Form: Ascites
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Clone: 10C8
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Antigen:
WNT1
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.:
__
Immunogen:
Purified recombinant fragment of human WNT1 expressed in E. Coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse
Form:
Ascites
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
10C8
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1