MilliporeSigma™ Neuroblasts, Armenian Hamster, Unlabeled, Clone: Nilo2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABD402MI-Each-of-1 | In Stock | ₹ 43,706.61 |
MABD402MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,706.61
GST (18%): ₹ 7,867.19
Total Price: ₹ 51,573.80
Antigen
Neuroblasts
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified Armenian hamster monoclonal antibody in PBS without preservatives.
Immunogen
E13.5 FVB mouse embryo olfactory bulb-derived neurospheres (Del Valle, I., et al. (2010). Neuroscience. 169(3):1473-1485).
Quantity
100 μg
Research Discipline
Stem Cell Research
Test Specificity
Nilo (Neural Identification Lineage from Olfactory bulb) monoclonal antibody Nilo2 (Mfr. No. MABD402) targets neuroblasts (Elvira, G., et al. (2012). PLoS One. 7(9):e44466), while Nilo1 (Mfr. No. MABD401) recognizes neural stem cells (NSCs; type B astrocytes) in adult mouse brain and radial glia in mouse embryo (Elvira, G., et al. (2015). Stem Cell Res. 14(1):114-129). Clone Nilo1 identified early progenitor cells (Sox2+, EGFR+, GFAP+ and vimentin+), whereas Nilo2 identified more differentiated neural progenitor cells committed to the neuroblast pathway (Tuj-1+, PSA-NCAM+ and DCX+). Nilo1 and Nilo2 arrest neurosphere proliferation in vitro and interfered with their differentiation into mature neural cells by targeting different surface glycoproteins highly relevant on neural stem/early progenitor cell biology (Del Valle, I., et al. (2010). Neuroscience. 169(3):1473-1485).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications
Immunohistochemistry, Immunoprecipitation, Inhibition Assays, Radioimmune Assays (RIA), Western Blot
Clone
Nilo2
Conjugate
Unconjugated
Host Species
Armenian Hamster
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse
Form
Purified
Related Products
Description
- Similar to other cell types, neural cells are generated from primary progenitor cells known as type B astrocytes or neural stem cells (NSCs) via stages of amplification (transient amplifying cells), resulting in the generation of intermediate precursor cells (iPCs) committed to neurons (nIPCs), astrocytes (aIPCs), or oligodendrocytes (oIPCs)
- In adult rodent brain, NSCs and iPCs are mainly restricted to niches in the subventricular zone (SVZ) of the lateral ventricles (LV)
- In the adult SVZ, type B cells (SVZB) generate neuroblasts (type A cells, neuronal precursors) through a highly proliferative transit amplifying population (type C cells)
- NSCs and iPCs paly important roles in neurogenesis in the adult brain
- Neuroblasts, for example, are known to migrate from their SVZ niche through the rostral migratory stream (RMS) to the olfactory bulb for the continuous generation of periglomerular interneurons
- In addition to maintaining the homeostasis of the olfactory bulb, both neuroblasts and NSCs are shown to mobilize from their SVZ niches to various brain damage sites caused by tumor growth, cryolesion, focal demyelinization, and mechanical lesion.
Compare Similar Items
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Antigen: Neuroblasts
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified Armenian hamster monoclonal antibody in PBS without preservatives.
Immunogen: E13.5 FVB mouse embryo olfactory bulb-derived neurospheres (Del Valle, I., et al. (2010). Neuroscience. 169(3):1473-1485).
Quantity: 100 μg
Research Discipline: Stem Cell Research
Test Specificity: Nilo (Neural Identification Lineage from Olfactory bulb) monoclonal antibody Nilo2 (Mfr. No. MABD402) targets neuroblasts (Elvira, G., et al. (2012). PLoS One. 7(9):e44466), while Nilo1 (Mfr. No. MABD401) recognizes neural stem cells (NSCs; type B astrocytes) in adult mouse brain and radial glia in mouse embryo (Elvira, G., et al. (2015). Stem Cell Res. 14(1):114-129). Clone Nilo1 identified early progenitor cells (Sox2+, EGFR+, GFAP+ and vimentin+), whereas Nilo2 identified more differentiated neural progenitor cells committed to the neuroblast pathway (Tuj-1+, PSA-NCAM+ and DCX+). Nilo1 and Nilo2 arrest neurosphere proliferation in vitro and interfered with their differentiation into mature neural cells by targeting different surface glycoproteins highly relevant on neural stem/early progenitor cell biology (Del Valle, I., et al. (2010). Neuroscience. 169(3):1473-1485).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Immunohistochemistry, Immunoprecipitation, Inhibition Assays, Radioimmune Assays (RIA), Western Blot
Clone: Nilo2
Conjugate: Unconjugated
Host Species: Armenian Hamster
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen: SIP1
Classification: Monoclonal
Concentration: 1mg/mL
Formulation: Purified mouse monoclonal IgG2aκ supernatant in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen: His-tagged recombinant protein corresponding to the N-terminus of Human SIP1.
Quantity: 100 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C for one year
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 6E5
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen: Cyp7a1
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen: GST-tagged recombinant protein corresponding to human Cyp7a1.
Quantity: 100 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C for one year
Applications: Immunohistochemistry, Western Blot
Clone: 15B9.1
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
