MABE1664MI
MilliporeSigma™ INK4b (p15), Mouse, Unlabeled, Clone: GF10 (10C7A6),
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE1664MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABE1664MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
INK4b (p15)
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Mouse monoclonal IgG1κ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.
P42772
Immunogen
Recombinant full-length human INK4b (p15).
Quantity
100 μL
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_004927
Target Species
Human
Form
Culture Supernatant
Applications
Western Blot
Clone
GF10 (10C7A6)
Conjugate
Unconjugated
Gene
CDKN2B, MTS2
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone GF10 (10C7A6), Mfr. No. MABE1664 and clone GF7 (7CIG4), Mfr. No. 05-430 correspond to two independent clones originated from the same mouse host. Clone GF10 (10C7A6) is recommended as an alternative to clone GF7 (7CIG4), however these two clones are expected to recognize different epitopes, exhibit different target-binding affinity and species cross-reactivity. Cross-reactivity of clone GF10 (10C7A6) toward spliced isoform 2 (p10; UniProt P42772-2) has not been confirmed.
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype
IgG1 κ
Related Products
Description
- Cyclin-dependent kinase 4 inhibitor B (UniProt P42772; also known as MTS-2, Multiple tumor suppressor 2, p14-INK4b, p15-INK4b, p15INK4B) is encoded by the CDKN2B (also known as MTS2) gene (Gene ID 1030) in human
- The INK and CIP/KIP families of cyclin dependent kinase inhibitors (CDKis) protect cells from oncogenic signals-initiated cellular transformation
- INK4a and INK4b (encoded by the CDKN2A and CDKN2B gene, respectively) constitute the INK4 subfamily of CDKis
- INK4a and INK4b are induced by oncogenic Ras and are involved in cell cycle G1 arrest and cellular senescence
- Inactivation of CDKN2A and CDKN2B are found in a wide variety of human malignancies and murine tumor models.
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Antigen: INK4b (p15)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Mouse monoclonal IgG1κ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.: P42772
Immunogen: Recombinant full-length human INK4b (p15).
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_004927
Target Species: Human
Form: Culture Supernatant
Applications: Western Blot
Clone: GF10 (10C7A6)
Conjugate: Unconjugated
Gene: CDKN2B, MTS2
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone GF10 (10C7A6), Mfr. No. MABE1664 and clone GF7 (7CIG4), Mfr. No. 05-430 correspond to two independent clones originated from the same mouse host. Clone GF10 (10C7A6) is recommended as an alternative to clone GF7 (7CIG4), however these two clones are expected to recognize different epitopes, exhibit different target-binding affinity and species cross-reactivity. Cross-reactivity of clone GF10 (10C7A6) toward spliced isoform 2 (p10; UniProt P42772-2) has not been confirmed.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
INK4b (p15)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Mouse monoclonal IgG1κ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.:
P42772
Immunogen:
Recombinant full-length human INK4b (p15).
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_004927
Target Species:
Human
Form:
Culture Supernatant
Applications:
Western Blot
Clone:
GF10 (10C7A6)
Conjugate:
Unconjugated
Gene:
CDKN2B, MTS2
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone GF10 (10C7A6), Mfr. No. MABE1664 and clone GF7 (7CIG4), Mfr. No. 05-430 correspond to two independent clones originated from the same mouse host. Clone GF10 (10C7A6) is recommended as an alternative to clone GF7 (7CIG4), however these two clones are expected to recognize different epitopes, exhibit different target-binding affinity and species cross-reactivity. Cross-reactivity of clone GF10 (10C7A6) toward spliced isoform 2 (p10; UniProt P42772-2) has not been confirmed.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Antigen: CCAR1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: GST/His-tagged recombinant fragment corresponding to 173 amino acids from the N-terminal half of human Cell division cycle and apoptosis regulator protein 1 (CCAR1).
Quantity: 25 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Applications: Western Blot, Immunocytochemistry
Clone: __
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4B9.1 detects Cell division cycle and apoptosis regulator protein 1 (CCAR1) in human cells. It targets an epitope witihin 173 amino acids from the N-terminal half.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b
Antigen:
CCAR1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
GST/His-tagged recombinant fragment corresponding to 173 amino acids from the N-terminal half of human Cell division cycle and apoptosis regulator protein 1 (CCAR1).
Quantity:
25 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunocytochemistry
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4B9.1 detects Cell division cycle and apoptosis regulator protein 1 (CCAR1) in human cells. It targets an epitope witihin 173 amino acids from the N-terminal half.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b
Antigen: PML Isoform II
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P29590-8
Immunogen: KLH-conjugated linear peptide corresponding to a C-terminal sequence of human PML Isoform II.
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_150242
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 1A8.1
Conjugate: Unconjugated
Gene: PML, MYL, PP8675, RNF71, TRIM19
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 1A8.1 was raised against an C-terminal region sequence unique to PML isoform II (PML-2), but not present in the other 11 PML spliced isoforms reported by UniProt (P29590).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
PML Isoform II
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P29590-8
Immunogen:
KLH-conjugated linear peptide corresponding to a C-terminal sequence of human PML Isoform II.
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_150242
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
1A8.1
Conjugate:
Unconjugated
Gene:
PML, MYL, PP8675, RNF71, TRIM19
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 1A8.1 was raised against an C-terminal region sequence unique to PML isoform II (PML-2), but not present in the other 11 PML spliced isoforms reported by UniProt (P29590).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: phospho-E2F1 (Ser375)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit monoclonal antibody IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 17 amino acids surrounding phosphoserine 375 from the C-terminal region of human transcription factor E2F1.
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_005216.1
Target Species: Human
Form: Purified
Applications: Western Blot, ELISA
Clone: 71-10
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 71-10 is a rabbit monoclonal antibody that specifically detects human E2F1 phosphorylated on Serine 375.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG
Antigen:
phospho-E2F1 (Ser375)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit monoclonal antibody IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 17 amino acids surrounding phosphoserine 375 from the C-terminal region of human transcription factor E2F1.
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_005216.1
Target Species:
Human
Form:
Purified
Applications:
Western Blot, ELISA
Clone:
71-10
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 71-10 is a rabbit monoclonal antibody that specifically detects human E2F1 phosphorylated on Serine 375.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG