MABS1262

MilliporeSigma™ phospho-ZIP7 (Ser275/276), Mouse, Unlabeled, Clone: 3-3-3,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1262-Each-of-1 In Stock ₹ 40,197.80

MABS1262 - Each of 1

₹ 40,197.80

In Stock

Quantity

1

Base Price: ₹ 40,197.80

GST (18%): ₹ 7,235.604

Total Price: ₹ 47,433.404

Antigen

phospho-ZIP7 (Ser275/276)

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q92504

Immunogen

KLH-conjugated phospho-peptide corresponding to the target region sequence with phosphorylated S256 and S257 residues.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_001070984

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

3-3-3

Conjugate

Unconjugated

Gene

SLC39A7, HKE4, RING5

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 3-3-3 reconizes S256/S257 dual phosphorylated wild-type ZIP7, as well as S256D/S257D, but not S256A/S257A, ZIP7 mutant.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Integrin beta-1 (UniProt P09055; also known as CD29, Fibronectin receptor subunit beta, GpIIa, VLA-1/2/3/4/5/6 subunit beta) is encoded by the Itgb1 (also known as Fnrb) gene (Gene ID 16412) in murine species
  • The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner
  • The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits
  • Key to these molecular interactions between the integrin receptors and their respective ligands is the recognition of the Arg-Gly-Asp (RGD) sequence known to be present in the extracellular matrix components fibronectin, vitronectin, collagen, fibrinogen, and von Willebrand factor
  • Integrin beta-1 is a 130kDa transmembrane glycoprotein that interact with various integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6) to form the functional receptor complexes that bind to specific extracellular matrix proteins
  • Integrin receptors regulate a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death
  • They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor growth and metastasis
  • These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and/or on adjacent cells
  • Interactions between integrins and the extracellular matrix lead to the activation of signal transduction pathways and regulation of gene expression.

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Show Difference

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MilliporeSigma™

MABS1262

--


Antigen:
phospho-ZIP7 (Ser275/276)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q92504

Immunogen:
KLH-conjugated phospho-peptide corresponding to the target region sequence with phosphorylated S256 and S257 residues.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001070984

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
3-3-3

Conjugate:
Unconjugated

Gene:
SLC39A7, HKE4, RING5

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 3-3-3 reconizes S256/S257 dual phosphorylated wild-type ZIP7, as well as S256D/S257D, but not S256A/S257A, ZIP7 mutant.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Img

Sigma Aldrich

MABS1266

clone 15C4, from mouse...


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__

Img

MilliporeSigma™

MABS1276MI

--


Antigen:
TRAP-1

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
Q12931

Immunogen:
Recombinant protein corresponding to human TRAP-1.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_057376.2

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
TR-1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG2a κ

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MABS1277MI

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Antigen:
Alix/Xp95

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q8WUM4

Immunogen:
GST-tagged recombinant full-length human Alix.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_037506

Target Species:
Human

Form:
Purified

Applications:
Immunoprecipitation, Western Blot

Clone:
1A3

Conjugate:
Unconjugated

Gene:
PDCD6IP, AIP1, ALIX, KIAA1375

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 1A3 recognizes an epitope conserved among human Alix and xenopus Xp95, localized within the Bro1 domain C-terminal end Patch 2 region (Zhou, X., et al. (2009). Biochem. J. 418(2):277-284). Clone 1A3 immunostained WI-30 cells before, but not after, siRNA-mediated Alix knockdown (Pan, S., et al. (2008). EMBO J. 27(15):2077-2090). Epitope region is present in human Alix spliced isoform 1 and 2 (equivalent to mouse isoform 1 and 3, respectively), but absent in isoform 3 (equivalent to mouse isoform 2) reported by UniProt (Q8WUM4 for human and Q9WU78 for mouse).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ