NBP248232
Melanoma Marker (MART-1 + gp100) Antibody (DT101+ BC199 + HMB45) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248232-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248232 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Melanoma Marker (MART-1 + gp100)
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with 0.05% BSA. with 0.05% Sodium Azide
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
2315
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
DT101+ BC199 + HMB45
Dilution
Immunohistochemistry-Paraffin
Gene Alias
MART1, MART-1
Immunogen
Recombinant hMART-1 protein (DT101& BC199); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Quantity
7 mL
Primary or Secondary
Primary
Test Specificity
This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage
Store at 4C.
Isotype
IgG2b κ, IgG1 κ
Related Products
Description
- Melanoma Marker (MART-1 + gp100) Monoclonal specifically detects Melanoma Marker (MART-1 + gp100) in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Melanoma Marker (MART-1 + gp100)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 2315
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: DT101+ BC199 + HMB45
Dilution: Immunohistochemistry-Paraffin
Gene Alias: MART1, MART-1
Immunogen: Recombinant hMART-1 protein (DT101& BC199); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage: Store at 4C.
Isotype: IgG2b κ, IgG1 κ
Antigen:
Melanoma Marker (MART-1 + gp100)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
2315
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
DT101+ BC199 + HMB45
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
MART1, MART-1
Immunogen:
Recombinant hMART-1 protein (DT101& BC199); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage:
Store at 4C.
Isotype:
IgG2b κ, IgG1 κ
Antigen: Cytokeratin, HMW
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 51350
Target Species: Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: AE-3
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CK-2P, cytokeratin 2, Cytokeratin-2P, HUMCYT2A, K2P, K76, keratin 76, keratin, type II cytoskeletal 2 oral, Keratin-76, KRT2Bcytokeratin-2P, KRT2Pkeratin 2p, KRT76, Type-II keratin Kb9
Immunogen: Human epidermal keratin (Uniprot: Q01546)
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Cytokeratin, HMW
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
51350
Target Species:
Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
AE-3
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CK-2P, cytokeratin 2, Cytokeratin-2P, HUMCYT2A, K2P, K76, keratin 76, keratin, type II cytoskeletal 2 oral, Keratin-76, KRT2Bcytokeratin-2P, KRT2Pkeratin 2p, KRT76, Type-II keratin Kb9
Immunogen:
Human epidermal keratin (Uniprot: Q01546)
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: NF-H
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 4744
Target Species: Human, Mouse, Rat, Porcine, Chicken
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: SPM203
Dilution: Immunohistochemistry-Paraffin
Gene Alias: 200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Immunogen: Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
NF-H
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
4744
Target Species:
Human, Mouse, Rat, Porcine, Chicken
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM203
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Immunogen:
Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: IgM Heavy Chain
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3507
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: Cocktail
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Constant region of heavy chain of IgM, Ig Mu Chain C Region BOT Ig Mu Chain C Region GAL Ig Mu Chain C Region OU immunoglobulin heavy constant mu, Immunoglobulin mu chain
Immunogen: Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This monoclonal antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Content And Storage: Store at 4C.
Isotype: IgG1 κ, IgG2b κ
Antigen:
IgM Heavy Chain
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3507
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
Cocktail
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Constant region of heavy chain of IgM, Ig Mu Chain C Region BOT Ig Mu Chain C Region GAL Ig Mu Chain C Region OU immunoglobulin heavy constant mu, Immunoglobulin mu chain
Immunogen:
Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This monoclonal antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ, IgG2b κ