PS1089100UL
MilliporeSigma™ anti-PhosphoDetect RhoA (pSer188), Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PS1089100UL-Each-of-1 | In Stock | ₹ 56,817.83 |
PS1089100UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,817.83
GST (18%): ₹ 10,227.209
Total Price: ₹ 67,045.039
Antigen
PhosphoDetect™ RhoA (pSer188)
Classification
Polyclonal
Formulation
In PBS, 1mg/mL BSA, 50% glycerol.
Immunogen
a synthetic peptide corresponding to amino acids surrounding the Ser188phosphorylation site of human RhoA, coupled to KLH
Regulatory Status
RUO
Test Specificity
Recognizes the ∽22kDa RhoA protein, expressed as a GST fusion protein (total ∽49kDa) and phosphorylatedin vitroby PKA.
Content And Storage
−20°C
Isotype
IgG
Applications
ELISA, Immunoblot, Immunoblot
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects PhosphoDetect™ RhoA (pSer 188 ) Clone: in Human samples, and it is validated for ELISA, Immuno Blotting Rho (A, B, and C) proteins are members of the Ras superfamily of GTPases
- They regulate a variety of cellular functions, including cell cycle progression, cytoskeletal rearrangement, and gene expression
- Rho cycles between the active GTP-bound form and the inactive GDP-bound form
- Conversion from the inactive to the active form and vice versa is controlled by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs)
- The three Rho proteins are highly homologous and contain the consensus sequences necessary for GDP/GTP binding and GTPase activity
- RhoA is phosphorylated at Ser 188 in vitro by PKA and PKG
- This phosphorylation enhances RhoGDI binding and inhibits RhoA-mediated stress fiber formation, indicating that Ser 188 is an important site for negative regulation of RhoA activity.
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Antigen: PhosphoDetect™ RhoA (pSer188)
Classification: Polyclonal
Formulation: In PBS, 1mg/mL BSA, 50% glycerol.
Immunogen: a synthetic peptide corresponding to amino acids surrounding the Ser188phosphorylation site of human RhoA, coupled to KLH
Regulatory Status: RUO
Test Specificity: Recognizes the ∽22kDa RhoA protein, expressed as a GST fusion protein (total ∽49kDa) and phosphorylatedin vitroby PKA.
Content And Storage: −20°C
Isotype: IgG
Applications: ELISA, Immunoblot, Immunoblot
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
PhosphoDetect™ RhoA (pSer188)
Classification:
Polyclonal
Formulation:
In PBS, 1mg/mL BSA, 50% glycerol.
Immunogen:
a synthetic peptide corresponding to amino acids surrounding the Ser188phosphorylation site of human RhoA, coupled to KLH
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽22kDa RhoA protein, expressed as a GST fusion protein (total ∽49kDa) and phosphorylatedin vitroby PKA.
Content And Storage:
−20°C
Isotype:
IgG
Applications:
ELISA, Immunoblot, Immunoblot
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
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