PK101050UL

MilliporeSigma™ anti-PhosphoDetect Syk (pTyr525/526), Polyclonal

Manufacturer: MilliporeSigma™

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Pack Size SKU Availability Price
Each of 1 PK101050UL-Each-of-1 In Stock ₹ 36,249.21

PK101050UL - Each of 1

₹ 36,249.21

In Stock

Quantity

1

Base Price: ₹ 36,249.21

GST (18%): ₹ 6,524.858

Total Price: ₹ 42,774.068

Antigen

PhosphoDetect™ Syk (pTyr525/526)

Classification

Polyclonal

Formulation

In 150mM NaCl, 10mM sodium HEPES, 100μg/mL BSA, 50% glycerol, pH 7.5.

Immunogen

a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr525/526phosphorylation sites of human Syk

Regulatory Status

RUO

Test Specificity

Recognizes the ∽72kDa Syk protein phosphorylated at Tyr525/526in human Syk or Tyr519/520in mouse Syk in 293T cells expressing wild-type Syk and CD8.

Content And Storage

−20°C

Isotype

IgG

Applications

ELISA, Immunoblot, Immunoblot

Conjugate

Unconjugated

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Purified

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Description

  • Specifically detects PhosphoDetect™ Syk (pTyr 525/526 ) Clone: in Human, Mouse samples, and it is validated for ELISA, Immuno Blotting Syk is a protein tyrosine kinase that is widely expressed and plays a key role in hematopoietic cell signaling
  • Syk is reported to interact with immunoreceptor tyrosine-based activation motifs (ITAMs) found in the cytoplasmic domains of immune receptors
  • This interaction serves to couple activated immune receptors to downstream signaling events that mediate diverse cellular responses, such as proliferation, differentiation, and phagocytosis
  • Syk is also reported to act as a potential tumor suppressor in human breast carcinomas
  • Phosphorylation of Tyr 525/526 , located in the activation loop of human Syk, is required for Syk activity.

Compare Similar Items

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MilliporeSigma™

PK101050UL

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Antigen:
PhosphoDetect™ Syk (pTyr525/526)

Classification:
Polyclonal

Formulation:
In 150mM NaCl, 10mM sodium HEPES, 100μg/mL BSA, 50% glycerol, pH 7.5.

Immunogen:
a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr525/526phosphorylation sites of human Syk

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽72kDa Syk protein phosphorylated at Tyr525/526in human Syk or Tyr519/520in mouse Syk in 293T cells expressing wild-type Syk and CD8.

Content And Storage:
−20°C

Isotype:
IgG

Applications:
ELISA, Immunoblot, Immunoblot

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Img

MilliporeSigma™

PK110950UL

--


Antigen:
PhosphoDetect™ Src Family (pTyr416)

Classification:
Polyclonal

Formulation:
In 150mM NaCl, 10mM sodium HEPES, 100μg/mL BSA, 50% glycerol, pH 7.5.

Immunogen:
a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr416phosphorylation site of human Src

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽60kDa Src protein phosphorylated at Tyr416in COLO 201 cells and PDGF-treated NIH/3T3 cells. May also recognize other Src family kinases phosphorylated at equivalent sites.

Content And Storage:
−20°C

Isotype:
IgG

Applications:
Immunoblot

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse, Rat, Xenopus species

Form:
Purified

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Sigma Aldrich

PKH26GL

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Img

Sigma Aldrich

PKH26PCL

Distributed for Phanos Technologies...


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