Description

• General description: Pyrene is made up of four fused benzol rings. It is an apolar molecule.[1] Phosphatidylethanolamine (PE), a phospholipid is found abundantly in mammalian cells. In mammals, 15-25% of the total lipid comprises of PE. It is enriched in the inner leaflet of membranes and is abundant in the inner mitochondrial membrane.[2]
• Application: 18:1 Pyrene PE may be used:as a quencher of protein intrinsic emission in intrinsic tryptophan quenching assays of membrane proximity[3]to incorporate in vesicle membranes[4]to label vesicles to confirm the presence of hybrid vesicles in flow-cytometric analysis[5]
• Biochem/physiol Actions: Phosphatidylethanolamine (PE) can serve as a lipid chaperone that supports in the folding of membrane proteins. It plays a key role in the activity of respiratory complexes. PE also participates in the initiation of autophagy.[2]
• Packaging: 5 mL Amber Glass Screw Cap Vial (810331P-1mg)