7114675
Tocris Bioscience™ Brequinar sodium
Potent and selective DHODH inhibitor.
Manufacturer: Fischer Scientific
CAS Number: 96201-88-6
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Chemical Name or Material
6-Fluoro-2-(2′-fluoro[1,1′-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium
Assay Percent Range
>99%
Molecular Formula
C23H14F2NO2Na
CAS
96201-88-6
Target
DHODH Inhibitors
Formula Weight
Observed MW: 397.35
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Brequinar sodium | Fischer Scientific | ₹ 13,432.92 | |
| | Tocris Bioscience™ Brequinar sodium | Fischer Scientific | ₹ 55,827.90 | |
 | Brequinar sodium | ChemScene | ₹ 16,769.76 - ₹ 75,378.36 | |
 | 96201-88-6 | Brequinar sodium | A2B Chem | ₹ 5,219.16 - ₹ 30,716.04 |
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Description
- Potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = ∽20 nM)
- Causes depletion of pyrimidine nucleotides
- Exhibits minimal inhibition against a panel of >400 kinases
- Triggers differentiation of AML cell lines (ED50 = ∽ 1 μM
- Note uridine concentration effects ED50 value)
- Causes differentiation and depletion of leukemia-initiating cells in vivo
- Antimetabolite.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: 6-Fluoro-2-(2′-fluoro[1,1′-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium
Assay Percent Range: >99%
Molecular Formula: C23H14F2NO2Na
CAS: 96201-88-6
Target: DHODH Inhibitors
Formula Weight: Observed MW: 397.35
Chemical Name or Material:
6-Fluoro-2-(2′-fluoro[1,1′-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium
Assay Percent Range:
>99%
Molecular Formula:
C23H14F2NO2Na
CAS:
96201-88-6
Target:
DHODH Inhibitors
Formula Weight:
Observed MW: 397.35
Chemical Name or Material: (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
Assay Percent Range: >99%
Molecular Formula: C21H20N4O3
CAS: 209783-80-2
Target: __
Formula Weight: Observed MW: 376.41
Chemical Name or Material:
(Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
Assay Percent Range:
>99%
Molecular Formula:
C21H20N4O3
CAS:
209783-80-2
Target:
__
Formula Weight:
Observed MW: 376.41
Chemical Name or Material: 4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Assay Percent Range: >99%
Molecular Formula: C20H22ClNO
CAS: 945714-67-0
Target: __
Formula Weight: Observed MW: 327.85
Chemical Name or Material:
4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Assay Percent Range:
>99%
Molecular Formula:
C20H22ClNO
CAS:
945714-67-0
Target:
__
Formula Weight:
Observed MW: 327.85
Chemical Name or Material: 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
Assay Percent Range: >98%
Molecular Formula: C27H31Br2ClN4O2
CAS: 193275-84-2
Target: __
Formula Weight: Observed MW: 638.82
Chemical Name or Material:
4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
Assay Percent Range:
>98%
Molecular Formula:
C27H31Br2ClN4O2
CAS:
193275-84-2
Target:
__
Formula Weight:
Observed MW: 638.82