7162953
VMAT1, Mouse anti-Mouse, Rat, Clone: N440/21, Millipore Sigma™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
VMAT1
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Neuroscience
Formulation
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% sodium azide, pH7.4 with 0.05% sodium azide.
Gene ID (Entrez)
NP_694694.1
Immunogen
Recombinant fragment corresponding to 93 amino acids from the N-terminal first lumenal region of murine Vesicular amine transporter 1 (VMAT1).
Primary or Secondary
Primary
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Clone
N440/21
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Rat, Mouse
Gene Alias
Chromaffin granule amine transporter;Solute carrier family 18 member 1;Vesicular amine transporter 1;VAT1
Gene Symbols
Scl18a1;Vmat1
Isotype
IgG1 κ
Purification Method
Protein G purified
Test Specificity
Clone N440/21 specifically detects Vesicular monoamine transporter 1 (VMAT1) and does not show reactivity with VMAT2. It targets an epitope with in 93 amino acids from the N-terminal first lumenal region.
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Description
- Anti-VMAT1, clone N440 21, Cat
- No
- MABN2547, is a highly specific mouse monoclonal antibody that targets Vesicular Monoamine Transporter 1 and has been tested for use in Western Blotting
- Chromaffin granule amine transporter (UniProt: Q8R090; also known as Solute carrier family 18 member 1, Vesicular amine transporter 1, VMAT1, VAT1) is encoded by the Scl19a1 (also known as Vmat1) gene (Gene ID: 110877) in murine species
- Vesicular monoamine transporters (VMATs) are involved in presynaptic storage and release of neurotransmitters
- They are located in the presynaptic region and are involved in the transport of monoamines into storage vesicle, which are released upon arrival of an action potential
- Two structurally related, but pharmacologically distinct, VMATs have been described (VMAT1 and VMAT2) that are encoded by separate genes
- VMAT1 is a multi-pass membrane acidic glycoprotein that is found in both large dense-core vesicles and in small synaptic vesicles
- It s both C- and N-terminal regions are located in the cytosolic side of the vesicle
- VMAT1 is detected in adrenal medulla, and brain (at protein level)
- In brain, specifically found in the medulla oblongata, pons, prefrontal cortex, striatum, dentate gyrus and hippocampus
- VMAT1 is shown to play a key role in survival of hippocampal neurons and may contribute to neurocognitive deficits observed in neuropsychiatric disorders
- (Ref.: Multani, PK., et al
- (2013)
- Neurosci
- 232; 32-44).
Compare Similar Items
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Antigen: VMAT1
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Neuroscience
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% sodium azide, pH7.4 with 0.05% sodium azide.
Gene ID (Entrez): NP_694694.1
Immunogen: Recombinant fragment corresponding to 93 amino acids from the N-terminal first lumenal region of murine Vesicular amine transporter 1 (VMAT1).
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: N440/21
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Rat, Mouse
Gene Alias: Chromaffin granule amine transporter;Solute carrier family 18 member 1;Vesicular amine transporter 1;VAT1
Gene Symbols: Scl18a1;Vmat1
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: Clone N440/21 specifically detects Vesicular monoamine transporter 1 (VMAT1) and does not show reactivity with VMAT2. It targets an epitope with in 93 amino acids from the N-terminal first lumenal region.
Antigen:
VMAT1
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Neuroscience
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% sodium azide, pH7.4 with 0.05% sodium azide.
Gene ID (Entrez):
NP_694694.1
Immunogen:
Recombinant fragment corresponding to 93 amino acids from the N-terminal first lumenal region of murine Vesicular amine transporter 1 (VMAT1).
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
N440/21
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Rat, Mouse
Gene Alias:
Chromaffin granule amine transporter;Solute carrier family 18 member 1;Vesicular amine transporter 1;VAT1
Gene Symbols:
Scl18a1;Vmat1
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
Clone N440/21 specifically detects Vesicular monoamine transporter 1 (VMAT1) and does not show reactivity with VMAT2. It targets an epitope with in 93 amino acids from the N-terminal first lumenal region.
Antigen: MULT1
Applications: ELISA, Flow Cytometry, Immunocytochemistry
Conjugate: Unconjugated
Host Species: Rat
Research Discipline: Signaling
Formulation: Purified rat monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene ID (Entrez): NA
Immunogen: Recombinant fragment corresponding to 186 amino acids from the extracellular domain of murine UL16-binding protein-like transcript 1 splicing variant (MULT-1).
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: 1D6
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: MULT-1;ULBP1;mouse UL16-binding protein-like Transcript 1;NKG2DL;NKG2D ligand
Gene Symbols: Ulbp1
Isotype: IgG2a κ
Purification Method: Protein G purified
Test Specificity: Clone 1D6 is a rat monoclonal antibody that detects UL16-binding protein-like transcript 1 splicing variant in mouse.
Antigen:
MULT1
Applications:
ELISA, Flow Cytometry, Immunocytochemistry
Conjugate:
Unconjugated
Host Species:
Rat
Research Discipline:
Signaling
Formulation:
Purified rat monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene ID (Entrez):
NA
Immunogen:
Recombinant fragment corresponding to 186 amino acids from the extracellular domain of murine UL16-binding protein-like transcript 1 splicing variant (MULT-1).
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
1D6
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
MULT-1;ULBP1;mouse UL16-binding protein-like Transcript 1;NKG2DL;NKG2D ligand
Gene Symbols:
Ulbp1
Isotype:
IgG2a κ
Purification Method:
Protein G purified
Test Specificity:
Clone 1D6 is a rat monoclonal antibody that detects UL16-binding protein-like transcript 1 splicing variant in mouse.
Antigen: Ketohexokinase Isoform C
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Signaling
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene ID (Entrez): NP_000212
Immunogen: A full-length human recombinant Ketohexokinase, isoform C.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: 5F1-3F5
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: EC: 2.7.1.3;Hepatic fructokinase;Fructokinase
Gene Symbols: KHK
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: Clone 5F1-3F5 specifically detects isoform C of human ketohexokinase.
Antigen:
Ketohexokinase Isoform C
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Signaling
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene ID (Entrez):
NP_000212
Immunogen:
A full-length human recombinant Ketohexokinase, isoform C.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
5F1-3F5
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
EC: 2.7.1.3;Hepatic fructokinase;Fructokinase
Gene Symbols:
KHK
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
Clone 5F1-3F5 specifically detects isoform C of human ketohexokinase.
Antigen: Ketohexokinase Isoform C
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Signaling
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene ID (Entrez): NP_000212
Immunogen: A full-length human recombinant Ketohexokinase, isoform C.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: 5F1-3F5
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: EC: 2.7.1.3;Hepatic fructokinase;Fructokinase
Gene Symbols: KHK
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: Clone 5F1-3F5 specifically detects isoform C of human ketohexokinase.
Antigen:
Ketohexokinase Isoform C
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Signaling
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene ID (Entrez):
NP_000212
Immunogen:
A full-length human recombinant Ketohexokinase, isoform C.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
5F1-3F5
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
EC: 2.7.1.3;Hepatic fructokinase;Fructokinase
Gene Symbols:
KHK
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
Clone 5F1-3F5 specifically detects isoform C of human ketohexokinase.