ABC973
MilliporeSigma™ BAG3, Chicken, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABC973-Each-of-1 | In Stock | ₹ 39,186.48 |
ABC973 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,186.48
GST (18%): ₹ 7,053.566
Total Price: ₹ 46,240.046
Antigen
BAG3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Bag3, Bis, MNCb-2243
Host Species
Chicken
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This chicken polyclonal antibody detects mouse BAG3 by targeting a C-terminal region sequence. Rat species cross-reactivity is likely, but has not been confirmed.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified chicken polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q9JLV1
Immunogen
KLH-conjugated linear peptide corresponding a sequence near the C-terminus of mouse BAG3.
Quantity
100 μg
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_0038891
Target Species
Mouse
Isotype
IgY
Related Products
Description
- BAG family molecular chaperone regulator 3 (UniProt Q9JLV1; also known as BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis) is encoded by the Bag3 (also known as Bis, MNCb-2243) gene (Gene ID 29810) in murine species
- Bcl-2-associated athanogene 3 (BAG3) is a stress-activated protein abundantly expressed in the heart, skeletal muscles, and many cancers
- BAG3 is involved in protein quality control (PQC) by serving as a co-chaperone for both constitutive and inducible heat shock proteins (Hsc/Hsp), as well as in mediating cellular anti-apoptotic activity via Bcl2 binding
- BAG3 also plays a role in sarcomere stability by regulating filamin clearance and production, as well as by interacting with actin capping protein beta 1 (CapZβ1) that binds the barbed end of actin and prevent actinn fibers from disssociating into actin monomers
- While BAG3 is found in the cytoplasm of neonatal myocytes and involved in PQC and apoptosis, BAG3 is localized predominantly in the sarcolemma and t-tubules of adult cardiac myocytes, where it modulates myocyte contraction in response to β-adrenergic receptor signaling
- Bag3-knock mice die 4 weeks after birth due to non-inflammatory myofibrillar degeneration
- Human BAG3 gene mutations are found in childhood-onset muscular dystrophy, in families with dilated cardiomyopathy, as well as in cases of idiopathic dilated cardiomyopathy.
Compare Similar Items
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Antigen: BAG3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bag3, Bis, MNCb-2243
Host Species: Chicken
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This chicken polyclonal antibody detects mouse BAG3 by targeting a C-terminal region sequence. Rat species cross-reactivity is likely, but has not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified chicken polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q9JLV1
Immunogen: KLH-conjugated linear peptide corresponding a sequence near the C-terminus of mouse BAG3.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_0038891
Target Species: Mouse
Isotype: IgY
Antigen:
BAG3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bag3, Bis, MNCb-2243
Host Species:
Chicken
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This chicken polyclonal antibody detects mouse BAG3 by targeting a C-terminal region sequence. Rat species cross-reactivity is likely, but has not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified chicken polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q9JLV1
Immunogen:
KLH-conjugated linear peptide corresponding a sequence near the C-terminus of mouse BAG3.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_0038891
Target Species:
Mouse
Isotype:
IgY
Antigen: Birc7/LIVIN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal serum in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to the BIR repeat region of human Birc7/LIVIN.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_647478
Target Species: Human
Isotype: __
Antigen:
Birc7/LIVIN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal serum in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to the BIR repeat region of human Birc7/LIVIN.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_647478
Target Species:
Human
Isotype:
__
Antigen: PRUNE
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human PRUNE.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NP_067045
Target Species: Human
Isotype: __
Antigen:
PRUNE
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human PRUNE.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NP_067045
Target Species:
Human
Isotype:
__
Antigen: __
Classification: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: purified
Regulatory Status: RUO - research use only
Primary or Secondary: __
Test Specificity: __
Content And Storage: -20°C. Avoid freeze-thaw cycles.
Applications: __
Concentration: 0.5 mg/mL
Formulation: peptide with no preservative
Gene Accession No.: __
Immunogen: __
Quantity: 50 μg
Research Discipline: __
Gene ID (Entrez): 25056
Target Species: __
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
purified
Regulatory Status:
RUO - research use only
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
-20°C. Avoid freeze-thaw cycles.
Applications:
__
Concentration:
0.5 mg/mL
Formulation:
peptide with no preservative
Gene Accession No.:
__
Immunogen:
__
Quantity:
50 μg
Research Discipline:
__
Gene ID (Entrez):
25056
Target Species:
__
Isotype:
__