ABE1332MI
MilliporeSigma™ monomethyl Histone H2A (Gln104), Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1332MI-Each-of-1 | In Stock | ₹ 44,990.87 |
ABE1332MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,990.87
GST (18%): ₹ 8,098.357
Total Price: ₹ 53,089.227
Antigen
monomethyl Histone H2A (Gln104)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Specificity of this polyclonal antibody was verified by dot blot analysis. This polyclonal antibody specifically detected peptide corresponding to histone H2A target region sequence with monomethylated Gln104 (Q104me), but not H2A peptides without Q104me modification, nor peptides derived from histone H1, H2A.Z, H2B, H3, H3.3, or H4 sequences.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Dot Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P0C0S8
Immunogen
KLH-conjugated linear peptide corresponding to human histone H2A target region sequence containing monomethylated Gln104 (Q104me).
Quantity
100 μL
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_003500
Target Species
Human
Related Products
Description
- Histone H2A type 1 (UniProt P0C0S8; also known as H2A.1, Histone H2A/p) is encoded by the HIST1H2AG (also known as H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN) gene (Gene ID 8969) in human
- Histone H2A is one of four components of the core nucleosome structure
- The nucleosome represents a unit of chromatin in which DNA is wrapped around a histone octamer
- Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
- DNA accessibility is regulated via a complex set of post-translational modifications of histones
- Histones undergo a number of post-translational modifications in response to various stimuli that may induce changes in the structure of the nucleosome and hide or expose DNA sequences
- Histone H2A, in particular, undergoes acetylation on lysine 5 by Tip60 enzyme, which may promote unfolding of chromatin and transcription
- In addition, H2A is phosphorylated on serine 1 and serine 139 (H2A.X) residues, which mark mitosis and gene repression and DNA damage, respectively
- Gene repression may also result from the sumoylation of H2A s lysine 126 residue
- In addition, ubiquitination of the H2A lysine 119 residue may play a role in spermatogenesis
- Monoubiquitination of Lys-120 (H2AK119Ub) by RING1, TRIM27 and RNF2/RING2 complex gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
Compare Similar Items
Show Difference
Antigen: monomethyl Histone H2A (Gln104)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Specificity of this polyclonal antibody was verified by dot blot analysis. This polyclonal antibody specifically detected peptide corresponding to histone H2A target region sequence with monomethylated Gln104 (Q104me), but not H2A peptides without Q104me modification, nor peptides derived from histone H1, H2A.Z, H2B, H3, H3.3, or H4 sequences.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Dot Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P0C0S8
Immunogen: KLH-conjugated linear peptide corresponding to human histone H2A target region sequence containing monomethylated Gln104 (Q104me).
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_003500
Target Species: Human
Antigen:
monomethyl Histone H2A (Gln104)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Specificity of this polyclonal antibody was verified by dot blot analysis. This polyclonal antibody specifically detected peptide corresponding to histone H2A target region sequence with monomethylated Gln104 (Q104me), but not H2A peptides without Q104me modification, nor peptides derived from histone H1, H2A.Z, H2B, H3, H3.3, or H4 sequences.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Dot Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P0C0S8
Immunogen:
KLH-conjugated linear peptide corresponding to human histone H2A target region sequence containing monomethylated Gln104 (Q104me).
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_003500
Target Species:
Human
Antigen: __
Classification: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Applications: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Applications:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Antigen: ZBTB4 (KAISO-L1)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects Zinc finger and BTB domain-containing protein 4 (KAISO-L1) in human cells. It targets an epitope within 17 amino acids from the internal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot, Immunohistochemistry (Paraffin)
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 17 amino acids from the internal region of human Zinc finger and BTB domain-containing protein 4.
Quantity: 25 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_001122305
Target Species: Human
Antigen:
ZBTB4 (KAISO-L1)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects Zinc finger and BTB domain-containing protein 4 (KAISO-L1) in human cells. It targets an epitope within 17 amino acids from the internal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 17 amino acids from the internal region of human Zinc finger and BTB domain-containing protein 4.
Quantity:
25 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_001122305
Target Species:
Human
Antigen: GATA-6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunocytochemistry, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: Set of 3 peptides designed against isoform 1 located between position 250-500). Note that peptide sequences used are also present in the isoform 2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_005248
Target Species: Human
Antigen:
GATA-6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunocytochemistry, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
Set of 3 peptides designed against isoform 1 located between position 250-500). Note that peptide sequences used are also present in the isoform 2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_005248
Target Species:
Human