ABE1451MI
MilliporeSigma™ phospho BRD4 (Ser492), Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1451MI-Each-of-1 | In Stock | ₹ 39,063.27 |
ABE1451MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,063.27
GST (18%): ₹ 7,031.389
Total Price: ₹ 46,094.659
Antigen
phospho BRD4 (Ser492)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BRD4, HUNK1, MCAP
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
The target phospho-serine residue is present in all human (pSer492) and murine (pSer493) BRD4 spliced isoforms reported by UniProt (O60885 and Q9ESU6). This polyclonal antibody is shown to exhibit stronger immunoreactivity toward BRD4 phosphopeptide with dual pSer492/494 (equivalent to mouse pSer493/495) phosphorylation than the corresponding peptide with only pSer492 (equivalent to mouse Ser493) phosphorylation (Korb, E., et al. (2015). Nat. Neurosci. 18(10):1464-1473).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Immunocytochemistry, Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
O60885
Immunogen
KLH-conjugated linear peptide corresponding to a human BRD4 sequence containing phosphorylated Ser492 (equivalent to mouse Ser493).
Quantity
100 μL
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_490597
Target Species
Human
Form
Purified
Related Products
Description
- Bromodomain-containing protein 4 (UniProt O60885; also known as MCAP, Mitotic chromosome-associated protein, Protein HUNK1) is encoded by the BRD4 (also known as HUNK1, MCAP) gene (Gene ID 23476) in human
- BRD4 is a BET (bromodomain and extra-terminal) protein family member that functions as a chromatin reader by binding acetylated lysines in histones
- BRD4 is an important transcription regulator in many cell types, including transcription in response to external cues
- BRD4 plays an essential role in neuronal function and mediates the transcriptional regulation underlying learning and memory
- BRD4 regulates IEG transcription in neurons upon phosphorylation by casein kinase 2 (CK2), which is activated in response to neuronal stimulation
- Brd4 knockout in mice is lethal, while Brd4 function blockage by inhibitor JQ1 (Cat
- No
- 500586) treatment is reported to affect the transcription of critical synaptic proteins, resulting in memory deficits and decreased seizure susceptibility in mice.
Compare Similar Items
Show Difference
Antigen: phospho BRD4 (Ser492)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRD4, HUNK1, MCAP
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The target phospho-serine residue is present in all human (pSer492) and murine (pSer493) BRD4 spliced isoforms reported by UniProt (O60885 and Q9ESU6). This polyclonal antibody is shown to exhibit stronger immunoreactivity toward BRD4 phosphopeptide with dual pSer492/494 (equivalent to mouse pSer493/495) phosphorylation than the corresponding peptide with only pSer492 (equivalent to mouse Ser493) phosphorylation (Korb, E., et al. (2015). Nat. Neurosci. 18(10):1464-1473).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunocytochemistry, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: O60885
Immunogen: KLH-conjugated linear peptide corresponding to a human BRD4 sequence containing phosphorylated Ser492 (equivalent to mouse Ser493).
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_490597
Target Species: Human
Form: Purified
Antigen:
phospho BRD4 (Ser492)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRD4, HUNK1, MCAP
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The target phospho-serine residue is present in all human (pSer492) and murine (pSer493) BRD4 spliced isoforms reported by UniProt (O60885 and Q9ESU6). This polyclonal antibody is shown to exhibit stronger immunoreactivity toward BRD4 phosphopeptide with dual pSer492/494 (equivalent to mouse pSer493/495) phosphorylation than the corresponding peptide with only pSer492 (equivalent to mouse Ser493) phosphorylation (Korb, E., et al. (2015). Nat. Neurosci. 18(10):1464-1473).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunocytochemistry, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
O60885
Immunogen:
KLH-conjugated linear peptide corresponding to a human BRD4 sequence containing phosphorylated Ser492 (equivalent to mouse Ser493).
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_490597
Target Species:
Human
Form:
Purified
Antigen: __
Classification: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Applications: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Applications:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Antigen: phospho Brd4 (Ser492/Ser494)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects Bromodomain-conntaining protein 4 phosphorylated at Ser492/Ser494. It targets an epitope of 14 amino acids in the N-terminal half.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunocytochemistry, Dot Blot, Western Blot, Immunohistochemistry
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 14 amino acids surrounding Ser492/Ser494 from the internal N-terminal half of human phospho Brd4 protein.
Quantity: 100 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_490597
Target Species: Human, Mouse, Rat, Porcine
Form: __
Antigen:
phospho Brd4 (Ser492/Ser494)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects Bromodomain-conntaining protein 4 phosphorylated at Ser492/Ser494. It targets an epitope of 14 amino acids in the N-terminal half.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunocytochemistry, Dot Blot, Western Blot, Immunohistochemistry
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 14 amino acids surrounding Ser492/Ser494 from the internal N-terminal half of human phospho Brd4 protein.
Quantity:
100 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_490597
Target Species:
Human, Mouse, Rat, Porcine
Form:
__
Antigen: NR4A1 (Nur77)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects Nuclear receptor subfamily 4 group A member 1 (NR4A1) in human, Monkey, and Murine cells It targets an epitope within 17 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot, Immunocytochemistry
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 17 amino acids from the N-terminal region of human Nuclear receptor subfamily 4 group A member 1 (NR4A1). The immunogen sequence is conserved in all 3 isoforms.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_001189162.1
Target Species: Monkey, Mouse, Human
Form: __
Antigen:
NR4A1 (Nur77)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects Nuclear receptor subfamily 4 group A member 1 (NR4A1) in human, Monkey, and Murine cells It targets an epitope within 17 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot, Immunocytochemistry
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 17 amino acids from the N-terminal region of human Nuclear receptor subfamily 4 group A member 1 (NR4A1). The immunogen sequence is conserved in all 3 isoforms.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_001189162.1
Target Species:
Monkey, Mouse, Human
Form:
__