ABS1513IYMI
MilliporeSigma™ phospho-Ubiquitin (Ser65), Rabbit, Alexa Fluor 488, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1513IYMI-Each-of-1 | In Stock | ₹ 43,706.61 |
ABS1513IYMI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,706.61
GST (18%): ₹ 7,867.19
Total Price: ₹ 51,573.80
Antigen
phospho-Ubiquitin (Ser65)
Classification
Polyclonal
Conjugate
Alexa Fluor 488
Gene
UBB, UBC
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Target specificity was verified using the unconjugated antibody (ABS1513-I). Only Ser65-phosphorylated ubiquitin (Ub) and ubiquitinated proteins (including oligoUb and polyUb) containing Ser65-phosphorylated ubiquitin were detected. This antibody exhibits no reactivity toward Ub or ubiquitinated proteins in the absence of Ub Ser65 phosphorylation.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Immunocytochemistry
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.
P0CG47;P0CG478
Immunogen
KLH-conjugated linear peptide corresponding to the ubiquitin target region sequence containing phosphorylated Ser65.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_061828;NP_066289
Target Species
Human
Form
Purified
Related Products
Description
- Lysine-specific demethylase 6A (UniProt O15550; also known as Histone demethylase UTX, KDM6A, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) is encoded by the KDM6A (also known as KABUK2, UTX) gene (Gene ID 7403) in human
- KDM6A specifically demethylates Lys-27 of histone H3 and plays a central role in histone code
- It is shown to demethylate trimethylated and dimethylated, but not monomethylated H3 Lys-27
- KDM6A plays a vital role in regulation of posterior development, by regulating HOX gene expression
- KDM6A also plays a potential role in regulating brown adipocyte thermogenic program
- It is up-regulated during brown adipocyte differentiation and by cold exposure in both brown and white adipose tissue in mice, indicating its potential role in thermogenesis
- Inactivation of KDM6A down-regulates brown fat specific gene expression
- Mutations in KDM6A gene are a causative factor in Kabuki syndrome that is characterized by congenital mental retardation, postnatal dwarfism, large prominent earlobes, a cleft or high-arched palate, scoliosis, and other abnormalities.
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Antigen: phospho-Ubiquitin (Ser65)
Classification: Polyclonal
Conjugate: Alexa Fluor 488
Gene: UBB, UBC
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Target specificity was verified using the unconjugated antibody (ABS1513-I). Only Ser65-phosphorylated ubiquitin (Ub) and ubiquitinated proteins (including oligoUb and polyUb) containing Ser65-phosphorylated ubiquitin were detected. This antibody exhibits no reactivity toward Ub or ubiquitinated proteins in the absence of Ub Ser65 phosphorylation.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunocytochemistry
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.: P0CG47;P0CG478
Immunogen: KLH-conjugated linear peptide corresponding to the ubiquitin target region sequence containing phosphorylated Ser65.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_061828;NP_066289
Target Species: Human
Form: Purified
Antigen:
phospho-Ubiquitin (Ser65)
Classification:
Polyclonal
Conjugate:
Alexa Fluor 488
Gene:
UBB, UBC
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Target specificity was verified using the unconjugated antibody (ABS1513-I). Only Ser65-phosphorylated ubiquitin (Ub) and ubiquitinated proteins (including oligoUb and polyUb) containing Ser65-phosphorylated ubiquitin were detected. This antibody exhibits no reactivity toward Ub or ubiquitinated proteins in the absence of Ub Ser65 phosphorylation.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunocytochemistry
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.:
P0CG47;P0CG478
Immunogen:
KLH-conjugated linear peptide corresponding to the ubiquitin target region sequence containing phosphorylated Ser65.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_061828;NP_066289
Target Species:
Human
Form:
Purified
Antigen: phospho- NFkB p52, (Ser222)
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: Q00653
Immunogen: KLH-conjugated linear peptide corresponding to the RHD domain of human phospho NFkB p52, (Ser222).
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_002493
Target Species: Human
Form: __
Antigen:
phospho- NFkB p52, (Ser222)
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
Q00653
Immunogen:
KLH-conjugated linear peptide corresponding to the RHD domain of human phospho NFkB p52, (Ser222).
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_002493
Target Species:
Human
Form:
__
Antigen: phospho-AKT1, Thr479
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects AKT1 phosphorylated on Thr479.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot, Inhibition Assays
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 10 amino acids surrounding Thr479 from the C-terminal region of human AKT1.
Quantity: 25 μg
Research Discipline: Signaling
Gene ID (Entrez): __
Target Species: Rat
Form: __
Antigen:
phospho-AKT1, Thr479
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects AKT1 phosphorylated on Thr479.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot, Inhibition Assays
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 10 amino acids surrounding Thr479 from the C-terminal region of human AKT1.
Quantity:
25 μg
Research Discipline:
Signaling
Gene ID (Entrez):
__
Target Species:
Rat
Form:
__
Antigen: AGS3/GPSM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gpsm1, Ags3
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antiserum immunostained predominantly renal collecting ducts of postnatal P12 ADPKD mice. Immunogen peptide blocking eliminated antibody stianing (Kwon, M., et al. (2012). Proc. Natl. Acad. Sci. U. S. A. 109(52):21462-21467). This antiserum targets a STK11/LKB1-interacting region sequence present in rat AGS3/GPSM1 isoform 1 and isoform 4 (isoform Long), 28% present in isoform 3 (Short-2), but completely absent from isoforms 2 (Short-1) reported by UniProt (Q9R080). Target sequence is also present in mouse isoforms 1, 3, 4, and 5, but absent from isoform 2 ( (UniProt Q6IR34).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.: Q9R080
Immunogen: Linear peptide corresponding to a sequence within the STK11/LKB1-interacting region of rat AGS3/GPSM1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_653346
Target Species: Mouse
Form: Serum
Antigen:
AGS3/GPSM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gpsm1, Ags3
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antiserum immunostained predominantly renal collecting ducts of postnatal P12 ADPKD mice. Immunogen peptide blocking eliminated antibody stianing (Kwon, M., et al. (2012). Proc. Natl. Acad. Sci. U. S. A. 109(52):21462-21467). This antiserum targets a STK11/LKB1-interacting region sequence present in rat AGS3/GPSM1 isoform 1 and isoform 4 (isoform Long), 28% present in isoform 3 (Short-2), but completely absent from isoforms 2 (Short-1) reported by UniProt (Q9R080). Target sequence is also present in mouse isoforms 1, 3, 4, and 5, but absent from isoform 2 ( (UniProt Q6IR34).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.:
Q9R080
Immunogen:
Linear peptide corresponding to a sequence within the STK11/LKB1-interacting region of rat AGS3/GPSM1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_653346
Target Species:
Mouse
Form:
Serum