ABE1943MI
MilliporeSigma™ Rabbit anti-HOXB13, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1943MI-Each-of-1 | In Stock | ₹ 41,813.98 |
ABE1943MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,813.98
GST (18%): ₹ 7,526.516
Total Price: ₹ 49,340.496
Antigen
HOXB13
Classification
Polyclonal
Gene Accession No.
Q92826
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-HCI, pH 8.0, and 0.1% soidum azide.
Gene Symbols
HOXB13
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of human HOXB13.
Quantity
100 μg
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_006352
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Related Products
Description
- Specifically detects HOXB13 in Human samples, and it is validated for Immunocytochemistry, Immunohistochemistry, Western Blotting Homeobox protein Hox-B13 (UniProt Q92826) is encoded by the HOXB13 (also known as PSGD) gene (Gene ID 10481) in human
- HOXB13 is a homeobox gene family member whose expression is restricted to prostate tissues and is highly correlated with that of androgen receptor (AR)
- Hox-B13 suppresses androgen-stimulated AR activity via direct AR interaction and thereby inhibits androgen-dependent (AD) prostate cancer (PCa) growth under androgen-rich conditions
- On the other hand, HOXB13 is also known to be over-expressed in castration-resistant PCa (CRPC), where it plays a dichotomic role in promoting androgen-independent (AI) PCa growth
- The zinc level in human prostate is markedly diminished in prostatic epithelial tumors and continues to decline during progression towards AI growth
- HOXB13 over-expression upregulates transcription of its target genes SLC30A10 (ZnT10) and SLC30A4 (ZnT4) for zinc output transporters, which are responsible for the reduction in zinc level in CRPC
- The diminished intracellular zinc level in turn stimulates NF-κB signaling and promotes invasion and metastasis of CRPC cells.
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Antigen: HOXB13
Classification: Polyclonal
Gene Accession No.: Q92826
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-HCI, pH 8.0, and 0.1% soidum azide.
Gene Symbols: HOXB13
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human HOXB13.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_006352
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
HOXB13
Classification:
Polyclonal
Gene Accession No.:
Q92826
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-HCI, pH 8.0, and 0.1% soidum azide.
Gene Symbols:
HOXB13
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human HOXB13.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_006352
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: Aprataxin
Classification: Polyclonal
Gene Accession No.: Q7Z2E3
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Immunoprecipitation, Western Blot
Formulation: Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols: APTX, AOA, AOA1, AXA1, EAOH, EOAHA
Immunogen: Recombinant full-length human aprataxin.
Quantity: 100 μL
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_001182177
Content And Storage: −20°C for one year
Antigen:
Aprataxin
Classification:
Polyclonal
Gene Accession No.:
Q7Z2E3
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Immunoprecipitation, Western Blot
Formulation:
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols:
APTX, AOA, AOA1, AXA1, EAOH, EOAHA
Immunogen:
Recombinant full-length human aprataxin.
Quantity:
100 μL
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_001182177
Content And Storage:
−20°C for one year
Antigen: __
Classification: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Applications: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Antigen:
__
Classification:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Applications:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Antigen: PRDM9
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Applications: Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: PRDM9;PFM6
Immunogen: GST-tagged recombinant fragment corresponding to 191 amino acids from the N-terminal half of human Histone-lysine N-methyltransferase PRDM9.
Quantity: 25 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
PRDM9
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
PRDM9;PFM6
Immunogen:
GST-tagged recombinant fragment corresponding to 191 amino acids from the N-terminal half of human Histone-lysine N-methyltransferase PRDM9.
Quantity:
25 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.