BDB558213
GITR Rat anti-Mouse, NA/LE, Unlabeled, Clone: DTA-1, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558213-Each-of-1 | In Stock | ₹ 59,036.40 |
BDB558213 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,036.40
GST (18%): ₹ 10,626.552
Total Price: ₹ 69,662.952
Antigen
GITR
Classification
Monoclonal
Concentration
1.0mg/mL
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
Mouse CD25+ CD4+ T Cell Line
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2b
Applications
Flow Cytometry
Clone
DTA-1
Conjugate
Unconjugated
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Related Products
Description
- The DTA-1 antibody reacts with GITR [Glucocorticoid-induced Tumor necrosis factor (TNF) receptor family-Related], a 66-70kDa homodimer glycoprotein that is a member of the TNF receptor superfamily and is also known as TNFRSF18
- As its name implies, GITR expression was first detected in T lymphocytes that had been treated with dexamethasone, a glucocorticoid
- In normal naive mice, GITR is expressed at moderate levels on CD25-positive/CD4-positive/CD8a-negative thymocytes and on CD25-positive/CD4-positive/CD45RB-low splenocytes
- It is also expressed at low levels on splenic CD25-negative/CD4-positive/CD45RB-low T lymphocytes, B lymphocytes, macrophages, and dendritic cells
- Activation of T and B lymphocytes upregulates GITR expression
- GITR is a costimulatory receptor that plays an important role in Regulatory T (Treg)-cell functions, and a GITR Ligand has been detected on B lymphocytes, macrophages, and dendritic cells
- mAb DTA-1 abrogates suppression by Treg cells without affecting their proliferative response, while it is co-stimulatory for T lymphocytes that are not Treg cells
- Host Species: Rat Clone: DTA-1 Isotype: IgG2b, λ Cross Reactivity: Bovine, Mouse Blocking Assay, Flow Cytometry
Compare Similar Items
Show Difference
Antigen: GITR
Classification: Monoclonal
Concentration: 1.0mg/mL
Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen: Mouse CD25+ CD4+ T Cell Line
Quantity: 0.5 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry
Clone: DTA-1
Conjugate: Unconjugated
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
GITR
Classification:
Monoclonal
Concentration:
1.0mg/mL
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen:
Mouse CD25+ CD4+ T Cell Line
Quantity:
0.5 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
DTA-1
Conjugate:
Unconjugated
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: CD3e
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Mouse T-cell receptor
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2 κ
Applications: Flow Cytometry
Clone: 500A2
Conjugate: Pacific Blue
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD3e
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Mouse T-cell receptor
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2 κ
Applications:
Flow Cytometry
Clone:
500A2
Conjugate:
Pacific Blue
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Histone H3 (pS28)
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Histone H3 Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Bovine, Fly, Hamster, Human, Mouse, Rat
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: HTA28
Conjugate: Alexa Fluor 647
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Histone H3 (pS28)
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Histone H3 Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Bovine, Fly, Hamster, Human, Mouse, Rat
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
HTA28
Conjugate:
Alexa Fluor 647
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: DCIR
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: __
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: I3-612
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
DCIR
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
I3-612
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.