BDB611803

ILK Mouse, Unlabeled, Clone: 3, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB611803-Each-of-1 In Stock ₹ 45,004.56

BDB611803 - Each of 1

₹ 45,004.56

In Stock

Quantity

1

Base Price: ₹ 45,004.56

GST (18%): ₹ 8,100.821

Total Price: ₹ 53,105.381

Antigen

ILK

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Human ILK aa. 326-452

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Chicken, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

3

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Integrins are transmembrane receptors that mediate cell-cell or cell-matrix adhesion
  • All integrins are heterodimers composed of α and β subunits, which interact with extracellular matrix and cytoskeletal proteins
  • Signal transduction through intergin receptors may be regulated by integrin-linked kinase (ILK)
  • ILK is a widely expressed Ser/Thr protein kinase that contains four ankyrin-like repeats in the N-terminal region, a phoshoinositide lipid-binding motif at amino acids 180-212, and an integrin binding site at amino acids 293-451
  • The ankyrin repeats interact with a LIM domain-only protein called PINCH that also binds the adaptor protein, Nck-2
  • This interaction implicates ILK in growth factor receptor pathways
  • In addition, the interaction of ILK with the cytoplasmic domains of integrin β1 and β3 subunits and localization of ILK to focal adhesion plaques suggests a role for ILK in the regulation of cell adhesion
  • Interestingly, overexpression of ILK in epithelial cells inhibits cell adhesion and stimulates cell cycle progression and tumorigenicity
  • Thus, ILK regulates signal transduction in many different cell signaling pathways
  • Host Species: Mouse Clone: 3 Isotype: IgG2 Species Reactivity [for Features Main]: Human Immunogen: Human ILK aa
  • 326-452 Immunofluorescence, Western Blotting

Compare Similar Items

Show Difference

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BD Biosciences

BDB611803

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Antigen:
ILK

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human ILK aa. 326-452

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
3

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Fischer Scientific

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Antigen:
Pericentrin

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse pericentrin aa. 1692-1814

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
30

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
Pericentrin

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse pericentrin aa. 1692-1814

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
30

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
Exportin-1 (CRM1)

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human hCRM1 aa. 2-122

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
17

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.