MAB342AF647
MilliporeSigma™ Galactocerebroside, Mouse, Alexa Fluor 647, Clone: mGalC,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MAB342AF647-Each-of-1 | In Stock | ₹ 53,734.25 |
MAB342AF647 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,734.25
GST (18%): ₹ 9,672.165
Total Price: ₹ 63,406.415
Antigen
Galactocerebroside
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG3 Alexa Fluor™ 647 conjugate in PBS with 1.5% BSA and 0.09% Sodium Azide.
Immunogen
Synaptic plasma membranes from bovine hippocampus (Ranscht, B. et al. (1982) Proc. Natl. Acad. Sci. U. S. A. 79(8):2709-2713).
Quantity
100 μL
Research Discipline
Neuroscience
Test Specificity
Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids. Cross-reacts with the sulfatide ester of GalC, but to a 16-fold lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically to the surface of oligodendrocytes and Schwann cells (Ranscht, B. et al. (1982) Proc. Natl. Acad. Sci. U. S. A. 79(8):2709-2713).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Immunocytochemistry
Clone
mGalC
Conjugate
Alexa Fluor 647
Host Species
Mouse
Purification Method
Protein A Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Bovine
Isotype
IgG3
Related Products
Description
- Galactocerebroside (GalCer or GalC) is the most frequently found glycosphingolipid in animals
- GalCer consist of a ceramide linked to a single galactose residue at the 1-hydroxyl moiety
- Cerebrosides are concentrated in nervous tissues where they increase from about 0.02% of the dry weight in human fetal brain to 2% in gray matter and 12% in white matter of adult brain
- GalCer is a specific cell-surface antigenic marker for oligodendrocytes and schwann cells
- GalCer is the largest single component of the myelin sheath of nerves
- GalCer synthesis therefore serves as a measurement of myelin formation or remyelination
- Krabbe disease is an autosomal recessive sphingolipidosis caused by deficient activity of the lysosomal hydrolase galactosylceramide beta-galactosidase (GALC)
- GALC mediates the degradation of GalCer and other terminal beta-Gal-containing sphingolipids, including psychosine (galactosylsphingosine)
- Increased psychosine levels are believed to lead to widespread destruction of oligodendroglia in the CNS and to subsequent demyelination.
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Antigen: Galactocerebroside
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG3 Alexa Fluor™ 647 conjugate in PBS with 1.5% BSA and 0.09% Sodium Azide.
Immunogen: Synaptic plasma membranes from bovine hippocampus (Ranscht, B. et al. (1982) Proc. Natl. Acad. Sci. U. S. A. 79(8):2709-2713).
Quantity: 100 μL
Research Discipline: Neuroscience
Test Specificity: Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids. Cross-reacts with the sulfatide ester of GalC, but to a 16-fold lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically to the surface of oligodendrocytes and Schwann cells (Ranscht, B. et al. (1982) Proc. Natl. Acad. Sci. U. S. A. 79(8):2709-2713).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunocytochemistry
Clone: mGalC
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Protein A Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Bovine
Isotype: IgG3
Antigen:
Galactocerebroside
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG3 Alexa Fluor™ 647 conjugate in PBS with 1.5% BSA and 0.09% Sodium Azide.
Immunogen:
Synaptic plasma membranes from bovine hippocampus (Ranscht, B. et al. (1982) Proc. Natl. Acad. Sci. U. S. A. 79(8):2709-2713).
Quantity:
100 μL
Research Discipline:
Neuroscience
Test Specificity:
Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids. Cross-reacts with the sulfatide ester of GalC, but to a 16-fold lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically to the surface of oligodendrocytes and Schwann cells (Ranscht, B. et al. (1982) Proc. Natl. Acad. Sci. U. S. A. 79(8):2709-2713).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunocytochemistry
Clone:
mGalC
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Protein A Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Bovine
Isotype:
IgG3
Antigen: Galactocerebroside
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal in buffer containing 10mM Potassium Phosphate, 150mM NaCl, pH 7.4 containing 0.09% sodium azide.
Immunogen: Synaptic plasma membranes from bovine hippocampus. Ranscht, B.et al.PNAS 79(8):2709-2713 (1982)
Quantity: 50 μg
Research Discipline: __
Test Specificity: __
Content And Storage: −20°C for up to 12 months.
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: mGalC
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein A purfied
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Bovine, Chicken, Human, Mouse, Rabbit, Rat
Isotype: IgG3
Antigen:
Galactocerebroside
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal in buffer containing 10mM Potassium Phosphate, 150mM NaCl, pH 7.4 containing 0.09% sodium azide.
Immunogen:
Synaptic plasma membranes from bovine hippocampus. Ranscht, B.et al.PNAS 79(8):2709-2713 (1982)
Quantity:
50 μg
Research Discipline:
__
Test Specificity:
__
Content And Storage:
−20°C for up to 12 months.
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
mGalC
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein A purfied
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Bovine, Chicken, Human, Mouse, Rabbit, Rat
Isotype:
IgG3
Antigen: CD28
Classification: Monoclonal
Concentration: __
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Immunogen: S. frugiperdainsect ovarian cell lineSf21-derived recombinant human CD28 Asn19-Pro152 Accession # P10747
Quantity: 25 μg
Research Discipline: Agonist Activity
Test Specificity: Detects human CD28 in Western blots. In Western blots, this antibody does not cross-react with recombinant mouse (rm) CD28, rhCTLA4, or rmCTLA4.
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Applications: Western Blot, In vitro Assay, Immunocytochemistry
Clone: 37407
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein A or G purified from ascites
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1
Antigen:
CD28
Classification:
Monoclonal
Concentration:
__
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Immunogen:
S. frugiperdainsect ovarian cell lineSf21-derived recombinant human CD28 Asn19-Pro152 Accession # P10747
Quantity:
25 μg
Research Discipline:
Agonist Activity
Test Specificity:
Detects human CD28 in Western blots. In Western blots, this antibody does not cross-react with recombinant mouse (rm) CD28, rhCTLA4, or rmCTLA4.
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Applications:
Western Blot, In vitro Assay, Immunocytochemistry
Clone:
37407
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein A or G purified from ascites
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1
Antigen: Desmin
Classification: Monoclonal
Concentration: __
Formulation: Liquid in 0.02Mphosphate buffer, 0.25M NaCl with 0.1% sodium azide, pH 7.6.
Immunogen: Purified desmin.
Quantity: 40 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C in undiluted aliquots for up to 12 months. Do not freeze.
Applications: Immunohistochemistry, Western Blot
Clone: DE-B-5
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: __
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Frog, Human, Mouse, Porcine, Rat
Isotype: IgG1
Antigen:
Desmin
Classification:
Monoclonal
Concentration:
__
Formulation:
Liquid in 0.02Mphosphate buffer, 0.25M NaCl with 0.1% sodium azide, pH 7.6.
Immunogen:
Purified desmin.
Quantity:
40 μg
Research Discipline:
__
Test Specificity:
__
Content And Storage:
2-8°C in undiluted aliquots for up to 12 months. Do not freeze.
Applications:
Immunohistochemistry, Western Blot
Clone:
DE-B-5
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Frog, Human, Mouse, Porcine, Rat
Isotype:
IgG1