MABF270MI

MilliporeSigma™ STING, Mouse, Unlabeled, Clone: S17G2C4B7,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF270MI-Each-of-1 In Stock ₹ 34,965.81

MABF270MI - Each of 1

₹ 34,965.81

In Stock

Quantity

1

Base Price: ₹ 34,965.81

GST (18%): ₹ 6,293.846

Total Price: ₹ 41,259.656

Antigen

STING

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q86WV6

Immunogen

His-tagged recombinant human STING C-terminal cytoplasmic domain fragment.

Quantity

100 μg

Research Discipline

Inflammation & Immunology

Gene ID (Entrez)

NP_938023.1

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

S17G2C4B7

Conjugate

Unconjugated

Gene

TMEM173, ERIS, MITA, MPYS, SAVI, STING

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone S17G2C4B7 recognizes an epitope in the C-terminal cytoplasmic domain of human and murine STING.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Stimulator of interferon genes protein (UniProt Q86WV6; also known as Endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, Mediator of IRF3 activation, Transmembrane protein 173) is encoded by the TMEM173 (also known as ERIS, MITA, MPYS, SAVI, STING) gene (Gene ID 340061) in human
  • STING is an adaptor protein activated by cytosolic dsDNA or cyclic dinucleotides and plays a critical role in initiating innate responses to infection by various pathogens, including Herpes simplex virus (HSV)
  • Once activated, STING translocates to the endoplasmic reticulum and activates the TBK1/IRF3 pathway that in turn mediates the upregulation of interferon (IFN) β
  • In addition, the DNA sensor IFI16 is also known to function as a STING ligand and potentiates STING-dependent sensing of viral infection by presenting cellular viral DNA to STING
  • STING is a four transmembrane (a.a
  • 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a
  • 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a
  • 153-340) with two c-di-GMP-binding regions (a.a
  • 162-167 and 238-241).

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MABF270MI

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Antigen:
STING

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q86WV6

Immunogen:
His-tagged recombinant human STING C-terminal cytoplasmic domain fragment.

Quantity:
100 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_938023.1

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
S17G2C4B7

Conjugate:
Unconjugated

Gene:
TMEM173, ERIS, MITA, MPYS, SAVI, STING

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone S17G2C4B7 recognizes an epitope in the C-terminal cytoplasmic domain of human and murine STING.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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Antigen:
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Classification:
Monoclonal

Concentration:
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Formulation:
Purified mouse monoclonal IgG2bκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_001229518

Immunogen:
Recombinant protein corresponding to human TREM-1.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
2(1a2)

Conjugate:
Atto 550

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for one year

Isotype:
IgG2b κ

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Antigen:
IL1F10 (IL-38)

Classification:
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Concentration:
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Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
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Immunogen:
His-tagged full-length recombinant human Interleukin-1 family member 10 (IL1F10).

Quantity:
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Research Discipline:
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Gene ID (Entrez):
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Target Species:
Human

Form:
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Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
H127C

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
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Content And Storage:
Stable for 1 year at +2°C to +8°C from date of receipt.

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IgG2b κ

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Antigen:
IL1F10 (IL-38)

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
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Immunogen:
His-tagged full-length recombinant human Interleukin-1 family member 10 (IL1F10).

Quantity:
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Research Discipline:
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Gene ID (Entrez):
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Target Species:
Human

Form:
Purified

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
H127C

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for 1 year at +2°C to +8°C from date of receipt.

Isotype:
IgG2b κ