NBP225208

B7-2/CD86 Antibody (BU63), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP225208-Each-of-1 In Stock ₹ 43,806.72

NBP225208 - Each of 1

₹ 43,806.72

In Stock

Quantity

1

Base Price: ₹ 43,806.72

GST (18%): ₹ 7,885.21

Total Price: ₹ 51,691.93

Antigen

B7-2/CD86

Classification

Monoclonal

Concentration

0.2 mg/ml

Dilution

Western Blot 0.5-1ug/ml, Flow Cytometry 1-2 ug/million cells, Immunohistochemistry 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 2-4 ug/ml, Immunohistochemistry-Frozen, Knockout Validated

Gene Alias

Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86

Host Species

Mouse

Molecular Weight of Antigen

70 kDa

Quantity

0.1 mg

Research Discipline

Adaptive Immunity, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology

Gene ID (Entrez)

942

Target Species

Human, Mouse, Rat

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoassay

Clone

BU63

Conjugate

Unconjugated

Gene Accession No.

NP_001193853

Gene Symbols

CD86

Immunogen

ARH-77 (B-lymphoblastoid cell line)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NBP229425

--

Img

Novus Biologicals

NBP229433

--

Img

Novus Biologicals

NBP229462

--

Img

Novus Biologicals

NBP229463

--

Img

Novus Biologicals

NBP229422

--

Img

Novus Biologicals

NBP229453

--

Img

Novus Biologicals

NBP229402

--

Img

Novus Biologicals

NBP229429

--

Description

  • B7-2/CD86 Monoclonal specifically detects B7-2/CD86 in Human, Mouse, Rat samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Functional, Knockout Validated.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP225208

--


Antigen:
B7-2/CD86

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 1-2 ug/million cells, Immunohistochemistry 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 2-4 ug/ml, Immunohistochemistry-Frozen, Knockout Validated

Gene Alias:
Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86

Host Species:
Mouse

Molecular Weight of Antigen:
70 kDa

Quantity:
0.1 mg

Research Discipline:
Adaptive Immunity, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology

Gene ID (Entrez):
942

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoassay

Clone:
BU63

Conjugate:
Unconjugated

Gene Accession No.:
NP_001193853

Gene Symbols:
CD86

Immunogen:
ARH-77 (B-lymphoblastoid cell line)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Fischer Scientific

NBP225220

--


Antigen:
CCR6

Classification:
Monoclonal

Concentration:
1.0 mg/ml

Dilution:
Western Blot 2-5 ug/ml, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 5 ug/ml

Gene Alias:
BN-1, CC-CKR-6, CCR-6, CD196 antigen, chemokine (C-C motif) receptor 6, CKR-L3G-protein coupled receptor 29, CKRL3LARC receptor, CMKBR6STRL22, DRY6, GPR29C-C CKR-6, GPRCY4DRY-6, lymphocyte, 22

Host Species:
Rat

Molecular Weight of Antigen:
__

Quantity:
0.1 mg

Research Discipline:
Chemokines and Cytokines, Cytokine Research, GPCR, Immunology, Innate Immunity, Signal Transduction

Gene ID (Entrez):
1235

Target Species:
Human, Mouse

Form:
Purified

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
18B9E6

Conjugate:
Unconjugated

Gene Accession No.:
NP_001177262

Gene Symbols:
CCR6

Immunogen:
A recombinant protein consisting of the external domains of mouse CD196 (CCR6) was used as the immunogen for the antibody.

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This product reacts with Mouse.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a κ

Img

Fischer Scientific

NBP225220SS

--


Antigen:
CCR6

Classification:
Monoclonal

Concentration:
1.0 mg/ml

Dilution:
Western Blot 2-5 ug/ml, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 5 ug/ml

Gene Alias:
BN-1, CC-CKR-6, CCR-6, CD196 antigen, chemokine (C-C motif) receptor 6, CKR-L3G-protein coupled receptor 29, CKRL3LARC receptor, CMKBR6STRL22, DRY6, GPR29C-C CKR-6, GPRCY4DRY-6, lymphocyte, 22

Host Species:
Rat

Molecular Weight of Antigen:
__

Quantity:
0.025 mg

Research Discipline:
Chemokines and Cytokines, Cytokine Research, GPCR, Immunology, Innate Immunity, Signal Transduction

Gene ID (Entrez):
1235

Target Species:
Human, Mouse

Form:
Purified

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
18B9E6

Conjugate:
Unconjugated

Gene Accession No.:
NP_001177262

Gene Symbols:
CCR6

Immunogen:
A recombinant protein consisting of the external domains of mouse CD196 (CCR6) was used as the immunogen for the antibody.

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This product reacts with Mouse.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a κ

Img

Novus Biologicals

NBP225221

--


Antigen:
MUC2

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Alias:
Intestinal mucin-2, MLP, MUC-2, mucin 2, intestinal/tracheal, mucin 2, oligomeric mucus/gel-forming, mucin-2, mucin-like protein, SMUC

Host Species:
Mouse

Molecular Weight of Antigen:
520 kDa

Quantity:
0.1 mg

Research Discipline:
Cancer, Cellular Markers, Inflammation, Signal Transduction

Gene ID (Entrez):
4583

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
CCP58

Conjugate:
Unconjugated

Gene Accession No.:
NP_002448

Gene Symbols:
MUC2

Immunogen:
A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH. (Uniprot: Q02817)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP(GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ