7223020
Tocris Bioscience™ CGI 1746
Potent, reversible BTK inhibitor
Manufacturer: Fischer Scientific
CAS Number: 910232-84-7
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Chemical Name or Material
N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide
Target
Brutons Tyrosine Kinase (BTK) Inhibitors
Purity
0.97
CAS
910232-84-7
Molecular Formula
C34H37N5O4
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ CGI 1746 | Fischer Scientific | ₹ 13,535.59 | |
| | Tocris Bioscience™ CGI 1746 | Fischer Scientific | ₹ 56,555.16 | |
 | N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide | Aaron Chemicals LLC | ₹ 6,160.32 - ₹ 30,288.24 | |
 | CGI-1746 | ChemScene | ₹ 5,989.20 - ₹ 24,812.40 | |
 | 910232-84-7 | Cgi-1746 | A2B Chem | ₹ 1,540.08 - ₹ 7,443.72 |
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Description
- CGI 1746 is a potent, reversible inhibitor of Bruton's tyrosine kinase (Btk) (IC50 = 1.9 nM)
- CGI 1746 decreases cell survival in prostate cancer cell lines
- In a cell model, CGI 1746 blocks the production of FcγR-induced cytokines IL-1β, TNFα and IL-6 (IC50 values are 36 nM, 47 nM and 353 nM, respectively).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide
Target: Brutons Tyrosine Kinase (BTK) Inhibitors
Purity: 0.97
CAS: 910232-84-7
Molecular Formula: C34H37N5O4
Chemical Name or Material:
N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide
Target:
Brutons Tyrosine Kinase (BTK) Inhibitors
Purity:
0.97
CAS:
910232-84-7
Molecular Formula:
C34H37N5O4
Chemical Name or Material: 6 '-Fluoro-2-[4-(4-methyl-4 H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3 '-bipyridine
Target: Other Transferase Inhibitors
Purity: 0.98
CAS: 2117405-13-5
Molecular Formula: C18H19FN6
Chemical Name or Material:
6 '-Fluoro-2-[4-(4-methyl-4 H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3 '-bipyridine
Target:
Other Transferase Inhibitors
Purity:
0.98
CAS:
2117405-13-5
Molecular Formula:
C18H19FN6
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