700040P

desmosterol-d6

Manufacturer: Sigma Aldrich

CAS Number: 1246298-67-8

Synonym(S): 24-dehydrocholesterol(d6); 5,24-cholestadien-3β-ol(d6)

Select a Size

Pack Size SKU Availability Price
1 MG 700040P-1-MG In Stock ₹ 51,278.03

700040P - 1 MG

₹ 51,278.03

In Stock

Quantity

1

Base Price: ₹ 51,278.03

GST (18%): ₹ 9,230.045

Total Price: ₹ 60,508.075

description

cholesta-5,24-dien-3β-ol-d6

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700040P-1mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

Other Options

Image Product Name Manufacturer Price Range
NC1613122
Avanti Polar Lipids Desmosterol-d6 | 1246298-67-8 | 390.7 g/mol |
Avanti Polar Lipids ₹ 47,111.05
AE39089
1246298-67-8 | Desmosterol-d6
A2B Chem ₹ 17,710.92

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Description

  • General description: Desmosterol constitutes 1% of brain sterol and is catabolized to cholesterol by the enzyme 3-hydroxysterol 24-reductase (DHCR24).[1] It is an intermediate in the Bloch branch of the cholesterol biosynthesis pathway.[2] Desmosterol-d6 is a deuterated form of desmosterol.
  • Application: Desmosterol-d6 has been used: as a deuterated standard in liquid chromatography multiple reaction monitoring (LC-MRM)[3] as a deuterated standard in high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC-ESI-MS)[4]for spiking brain tissue homogenate from Alzheimer′s disease (AD) for liquid chromatography -mass spectrometry (LC-MS) analysis[5]
  • Biochem/physiol Actions: Desmosterol low levels in the hippocampus directly impacts progenitor cell differentiation into neurons.[1] Desmosterol-d6 is used as a substitute to desmosterol in hepatitis C virus (HCV) based viral assays to rescue replication.[2] Desmosterol being a C27 sterol intermediate is implicated in the Alzheimer′s disease (AD) pathogenesis.[5]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700040P-1mg)

Compare Similar Items

Show Difference

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Sigma Aldrich

700040P

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description:
cholesta-5,24-dien-3β-ol-d6

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (700040P-1mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

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Sigma Aldrich

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description:
cholest-5-en-3β,7β-diol-d7

Assay:
>99% (TLC)

form:
powder

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pkg of 1 × 1 mg (700044P-1mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

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Sigma Aldrich

700045

≥97%...


description:
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Assay:
≥97%

form:
powder

packaging:
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manufacturer/tradename:
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shipped in:
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storage temp.:
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Sigma Aldrich

700046P

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description:
3β-hydroxy-5-cholestene-7-one-d7

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (700046P-1mg)pkg of 1 × 5 mg (700046P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C