SML1277

Geldanamycin-FITC

≥98% (HPLC), from Streptomyces hygroscopicus

Manufacturer: Sigma Aldrich

Synonym(S): Geldanamycin, fluorescein isothiocyanate labeled

Select a Size

Pack Size SKU Availability Price
1 MG SML1277-1-MG In Stock ₹ 27,733.65

SML1277 - 1 MG

₹ 27,733.65

In Stock

Quantity

1

Base Price: ₹ 27,733.65

GST (18%): ₹ 4,992.057

Total Price: ₹ 32,725.707

biological source

Streptomyces hygroscopicus

Quality Level

200

Assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

yellow to yellow-orange

solubility

DMSO: soluble 5 mg/mL

antibiotic activity spectrum

neoplastics

Mode of action

enzyme | inhibits

storage temp.

−20°C

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Description

  • General description: Chemical structure: benzenoid
  • Biochem/physiol Actions: Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines. Geldanamycin binds specifically to the heat shock protein Hsp90 and to its endoplasmic reticulum homologue GP96, and thus interferes with conformational maturation of proteins and the cellular stress response. In addition, Geldanamycin is a potent inhibitor of the nuclear hormone receptor family.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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biological source:
Streptomyces hygroscopicus

Quality Level:
200

Assay:
≥98% (HPLC)

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powder

storage condition:
protect from light

color:
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solubility:
DMSO: soluble 5 mg/mL

antibiotic activity spectrum:
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