ABT1487MI
MilliporeSigma™ alpha-Actin, Smooth Muscle, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT1487MI-Each-of-1 | In Stock | ₹ 41,643.76 |
ABT1487MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,643.76
GST (18%): ₹ 7,495.877
Total Price: ₹ 49,139.637
Antigen
alpha-Actin, Smooth Muscle
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ACTA2, AAT6, ACTSA, ACTVS, GIG46, MYMY5
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antibody targets the N-terminal sequence specific to smooth muscle alpha-actin (ACTA2), but not skeletal muscle alpha-actin (ACTA1), cytoplasmic beta-actin (ACTB), cardiac muscle alpha-actin (ACTC1), cytoplasmic gamma-actin (ACTG1), or smooth muscle gamma-actin (ACTG2; ACTA3).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P62736
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminual sequence of human smooth muscle alpha-actin.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001135417
Target Species
Human
Related Products
Description
- Actin, aortic smooth muscle (UniProt P62736; also known as Alpha-actin-2, Cell growth-inhibiting gene 46 protein) is encoded by the ACTA2 (also known as AAT6, ACTSA, ACTVS, GIG46, MYMY5) gene (Gene ID 59) in human
- Actins are globular multi-functional proteins that serve as the basic building blocks of cytoskeletal microfilaments and are among the most conserved eukaryotic proteins
- Six actin types exist, skeletal muscle alpha-actin is encoded by the ACTA1 gene, smooth muscle alpha-actin by the ACTA2 gene, cytoplasmic beta-actin by the ACTB gene, cardiac muscle alpha-actin by the ACTC1 gene, cytoplasmic gamma-actin by the ACTG1 gene, and smooth muscle gamma-actin by the ACTG2 (a.k.a
- ACTA3) gene
- Although actins show 90% overall sequence homology, isoforms do show spatial, temporal, and tissue-specific expresson patterns and only 50-60% homology is found in their 18 N-terminal residues
- Cytoplasmic β and γ-actins, are thought to be present in all cells, while the other four actin isoforms are typically found in specific adult muscle tissue types
- Actins exist in a variety of structural states, depending on the specific ionic conditions or the interaction with ligand proteins
- The oligomeric and polymeric forms that actin molecules assume are dependent on the distinct conformations they adopt.
Compare Similar Items
Show Difference
Antigen: alpha-Actin, Smooth Muscle
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACTA2, AAT6, ACTSA, ACTVS, GIG46, MYMY5
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody targets the N-terminal sequence specific to smooth muscle alpha-actin (ACTA2), but not skeletal muscle alpha-actin (ACTA1), cytoplasmic beta-actin (ACTB), cardiac muscle alpha-actin (ACTC1), cytoplasmic gamma-actin (ACTG1), or smooth muscle gamma-actin (ACTG2; ACTA3).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P62736
Immunogen: KLH-conjugated linear peptide corresponding to the N-terminual sequence of human smooth muscle alpha-actin.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001135417
Target Species: Human
Antigen:
alpha-Actin, Smooth Muscle
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACTA2, AAT6, ACTSA, ACTVS, GIG46, MYMY5
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody targets the N-terminal sequence specific to smooth muscle alpha-actin (ACTA2), but not skeletal muscle alpha-actin (ACTA1), cytoplasmic beta-actin (ACTB), cardiac muscle alpha-actin (ACTC1), cytoplasmic gamma-actin (ACTG1), or smooth muscle gamma-actin (ACTG2; ACTA3).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P62736
Immunogen:
KLH-conjugated linear peptide corresponding to the N-terminual sequence of human smooth muscle alpha-actin.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001135417
Target Species:
Human
Antigen: MCAM/CD146
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MCAM, MUC18
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both spliced isoforms of human MCAM/CD146 reported by UniProt (P43121).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunoprecipitation, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P43121
Immunogen: KLH-conjugated linear peptide corresponding to a sequence from the third C2-type Ig-like domain of human MCAM/CD146.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_006491
Target Species: Human
Antigen:
MCAM/CD146
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MCAM, MUC18
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both spliced isoforms of human MCAM/CD146 reported by UniProt (P43121).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunoprecipitation, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P43121
Immunogen:
KLH-conjugated linear peptide corresponding to a sequence from the third C2-type Ig-like domain of human MCAM/CD146.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_006491
Target Species:
Human
Antigen: Claudin-11
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_005593
Target Species: Human
Antigen:
Claudin-11
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_005593
Target Species:
Human
Antigen: Cofilin-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CFL, CFL1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P23528
Immunogen: KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_005498
Target Species: Human
Antigen:
Cofilin-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CFL, CFL1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P23528
Immunogen:
KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_005498
Target Species:
Human