ABT264MI
MilliporeSigma™ anti-beta Actin, Polyclonal
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT264MI-Each-of-1 | In Stock | ₹ 45,381.02 |
ABT264MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,381.02
GST (18%): ₹ 8,168.584
Total Price: ₹ 53,549.604
Antigen
beta Actin
Classification
Polyclonal
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ACTB
Immunogen
C-terminally KLH-conjugated linear peptide corresponding to human beta-actin N-terminal sequence with arginylation modification.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001092
Target Species
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Gene Accession No.
P60709
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antibody detects beta-actin posttranslationally modified by the removal of Met1 and Asp 2 and the arginylation of Asp3. This antibody does not react with beta-actin with unmodified N-terminus.
Content And Storage
2°C to 8°C for one year
Related Products
Description
- Specifically detects beta Actin Clone: in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Western Blotting Actin, cytoplasmic 1 (UniProt P60709; also known as beta-actin, PS1TP5-binding protein 1) is encoded by the ACTB (also known as BRWS1, PS1TP5BP1) gene (Gene ID 60) in human
- Post-translational protein arginylation is mediated by Arg–transfer RNA (-tRNA) protein transferase (Ate1; arginyltransferase).β- andγ-actins are the major structural components of the actin cytoskeleton in nonmuscle cells
- Despite their similarity, theβ-, but not theγ-, actin is N-terminally arginylated in vivo, where the first two N-terminal amino acids are removed and replaced with an arginine (from NH2-MDDDIAAL- to NH2-RDDIAAL-)
- In the absence of arginylation, actin forms aggregates during cell-free polymerization
- Fibroblasts derived from Ate1 knockout (KO) mice show collapsed lamella, which can be rescued by reintroducing N-terminally arginylatedβ-actin into the Ate1 KO cells
- Intracellular actin polymer levels are shown to drastically decrease in arginylation-deficient cells, which results from changes in actin polymerization properties.
Compare Similar Items
Show Difference
Antigen: beta Actin
Classification: Polyclonal
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ACTB
Immunogen: C-terminally KLH-conjugated linear peptide corresponding to human beta-actin N-terminal sequence with arginylation modification.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001092
Target Species: Human, Mouse, Rat
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Gene Accession No.: P60709
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody detects beta-actin posttranslationally modified by the removal of Met1 and Asp 2 and the arginylation of Asp3. This antibody does not react with beta-actin with unmodified N-terminus.
Content And Storage: 2°C to 8°C for one year
Antigen:
beta Actin
Classification:
Polyclonal
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ACTB
Immunogen:
C-terminally KLH-conjugated linear peptide corresponding to human beta-actin N-terminal sequence with arginylation modification.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001092
Target Species:
Human, Mouse, Rat
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
P60709
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody detects beta-actin posttranslationally modified by the removal of Met1 and Asp 2 and the arginylation of Asp3. This antibody does not react with beta-actin with unmodified N-terminus.
Content And Storage:
2°C to 8°C for one year
Antigen: Dynein, HC, cytosolic
Classification: Polyclonal
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: KLH-conjugated linear peptide corresponding to a sequence within the second AAA domain of human cytoplasmic dynein heavy chain.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001367
Target Species: Human
Applications: Western Blot
Conjugate: Unconjugated
Gene Accession No.: Q14204
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody targets a sequence within the second AAA domain of cytoplasmic dynein heavy chain encoded by the DYNC1H1 gene.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Antigen:
Dynein, HC, cytosolic
Classification:
Polyclonal
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
KLH-conjugated linear peptide corresponding to a sequence within the second AAA domain of human cytoplasmic dynein heavy chain.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001367
Target Species:
Human
Applications:
Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
Q14204
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody targets a sequence within the second AAA domain of cytoplasmic dynein heavy chain encoded by the DYNC1H1 gene.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Antigen: CELSR3
Classification: Polyclonal
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CELSR3; CDHF11; EGFL1; FMI1; MEGF2
Immunogen: KLH-conjugated linear peptide corresponding to the cytoplasmic domain within the C-terminus of human CELSR3.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_001398
Target Species: Human
Applications: Immunohistochemistry
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Antigen:
CELSR3
Classification:
Polyclonal
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CELSR3; CDHF11; EGFL1; FMI1; MEGF2
Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain within the C-terminus of human CELSR3.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_001398
Target Species:
Human
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Antigen: Liprin Alpha 1
Classification: Polyclonal
Formulation: __
Gene Symbols: PPFIA1,LIP1
Immunogen: GST-tagged recombinant fragment of 179 amino acids from the internal region of human Liprin Alpha 1.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_003617,NP_803172
Target Species: Human
Applications: Western Blot
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody detects Liprin Alpha 1 in human. It targets an epitope within 179 amino acids from the internal region of isoform 1 and 2.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
Liprin Alpha 1
Classification:
Polyclonal
Formulation:
__
Gene Symbols:
PPFIA1,LIP1
Immunogen:
GST-tagged recombinant fragment of 179 amino acids from the internal region of human Liprin Alpha 1.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_003617,NP_803172
Target Species:
Human
Applications:
Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody detects Liprin Alpha 1 in human. It targets an epitope within 179 amino acids from the internal region of isoform 1 and 2.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.