BDB556349
MSH-2 Mouse anti-Human, Unlabeled, Clone: G219-1129, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB556349-Each-of-1 | In Stock | ₹ 30,929.94 |
BDB556349 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,929.94
GST (18%): ₹ 5,567.389
Total Price: ₹ 36,497.329
Antigen
MSH-2
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Recombinant Human MSH2 Protein
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1
Applications
Western Blot
Clone
G219-1129
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- The repair of mismatched DNA is essential to maintaining the integrity of genetic information over time
- In bacteria the DNA repair process is accomplished by the MutL, MutH, and MutS proteins
- The MutS protein initially recognizes and binds to mismatched DNA
- Following this, MutH, an endonuclease, and MutL form a complex with MutS and carry out an excision repair mechanism
- When bacteria are deficient in one of these enzymes a mutator phenotype arises characterized by genetic instability
- The important role played by DNA repair enzymes is emphasized by the fact that they are highly conserved from bacteria to yeast to mammals
- In yeast the proteins are called MutS homolog 2 (MSH2), MutL homolog (MLH1), and PMS1 which is also a homolog of MutL
- MSH2 is involved in the initial recognition of mismatched nucleotides during the replication mismatch repair process
- It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMS1 which together help facilitate the later steps in mismatch repair
- The human homologs of DNA mismatch repair enzymes MLH1, PMS2, and MSH2 have recently been cloned
- G219-1129 recognizes human MSH-2
- A recombinant full-length human MSH2 protein was used as immunogen
- Host Species: Mouse Clone: G219-1129 Isotype: IgG1 Species Reactivity: Human Immunogen: Recombinant Human MSH2 Protein Immunohistochemistry, Immunohistochemistry (Frozen), Western Blotting
Compare Similar Items
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Antigen: MSH-2
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Recombinant Human MSH2 Protein
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: G219-1129
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
MSH-2
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Recombinant Human MSH2 Protein
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
G219-1129
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: Calcineurin
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human β1 isoform of calcineurin A Subunit aa. 349-505
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: G182-1847
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Calcineurin
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human β1 isoform of calcineurin A Subunit aa. 349-505
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
G182-1847
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: MDM2
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human MDM2 aa. 154-167 Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: SMP14
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
MDM2
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human MDM2 aa. 154-167 Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
SMP14
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: Bcl-2 w/control
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Bcl-2 synthetic peptide aa. 41-54
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Flow Cytometry
Clone: BCL-2/100
Conjugate: FITC
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Bcl-2 w/control
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Bcl-2 synthetic peptide aa. 41-54
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
BCL-2/100
Conjugate:
FITC
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.