BDB611002

Dynactin p50 Mouse, Unlabeled, Clone: 25, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB611002-Each-of-1 In Stock ₹ 22,587.84

BDB611002 - Each of 1

₹ 22,587.84

In Stock

Quantity

1

Base Price: ₹ 22,587.84

GST (18%): ₹ 4,065.811

Total Price: ₹ 26,653.651

Antigen

Dynactin p50

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Human Dynactin p50 aa. 55-196

Quantity

50 μg

Research Discipline

Cell Biology

Target Species

Drosophila, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

25

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Dyneins are ubiquitous, multimeric proteins that are responsible for minus end-directed microtubule-based organelle transport
  • They are divided into two classes, cytosolic and axonemal
  • The activity of cytosolic dynein is regulated by the multiprotein dynactin complex with which it co-purifies
  • Dynactin is composed of at least nine polypeptides with p50 being the second most abundant subunit
  • The complex consists of an F-actin-like core filament of actin-related protein Arp1, a heterodimer that acts as a cap at one end, and a 62kDa subunit at the other end
  • p150[glued] is the largest subunit of the complex
  • The precise function of dynactin remains to be determined, but it may be recruited to prometaphase kinetochores to assist in alignment and spindle organization during mitosis
  • Additionally, dynactin localizes at the tail of cytosolic dynein and activates dynein-mediated vesicle movement
  • Therefore, dynactin may function to anchor or target dynein to the kinetochore during mitosis.

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Show Difference

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BDB611002

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Antigen:
Dynactin p50

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Dynactin p50 aa. 55-196

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Drosophila, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
25

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
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Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human CD51/VNRα aa. 609-722

Quantity:
50 μg

Research Discipline:
Immunology

Target Species:
Canine, Human, Mouse, Rat

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
21

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

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Store undiluted at -20°C.

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Antigen:
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Immunogen:
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Quantity:
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Research Discipline:
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Target Species:
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Isotype:
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Applications:
Western Blot

Clone:
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Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Concentration:
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Formulation:
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Immunogen:
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Quantity:
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Research Discipline:
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Target Species:
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Isotype:
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Applications:
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Clone:
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Conjugate:
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Host Species:
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Purification Method:
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Regulatory Status:
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Primary or Secondary:
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Content And Storage:
Store undiluted at -20°C.