BDB611504
IGFBP-3 Mouse anti-Human, Unlabeled, Clone: 4, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB611504-Each-of-1 | In Stock | ₹ 23,956.80 |
BDB611504 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,956.80
GST (18%): ₹ 4,312.224
Total Price: ₹ 28,269.024
Antigen
IGFBP-3
Classification
Monoclonal
Concentration
250μg/mL
Description
IGF-Binding Protein-3
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Applications
Western Blot
Clone
4
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human IGFBP-3 aa. 101-210
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1
Related Products
Description
- Insulin-like growth factors (IGF) I and II are peptide hormones that regulate cellular proliferation and differentiation
- Most circulating IGFs exist in 130-150kDa ternary complexes containing IGF-Binding Protein-3 (IGFBP-3) and an 85kDa glycoprotein, the acid-labile subunit (ALS)
- IGFBP-3 is one of six IGFBPs that, by binding IGF peptides, prolong their half life and maintain the IGF reservoir
- IGFBP-3 is found in body fluids as multiple 40-50kDa forms as a result of differential glycosylation
- The expression of IGFBP-3 in many tissues suggests that it locally modulates the autocrine/paracrine action of IGF peptides
- IGFBP-3 binding to fibrinogen may be important for wound healing, since this concentrates IGF-I at wound sites and lowers the affinity of IGF-I for IGFBP-3
- In addition, retinoic acid-induced IGFBP-3 expression inhibits the growth promoting effects of IGF-I in breast cancer cells
- This may link the retinoid and IGF systems in cell growth regulation and explain how the loss of retinoic acid receptor β leads to breast cancer progression
- Thus, IGFBP-3 maintenance and regulation of IGF activity in various tissues may have diverse physiological roles
- Host Species: Mouse Clone: 4 Isotype: IgG1 Species Reactivity: Human Immunogen: Human IGFBP-3 aa
- 101-210 Formula Weight [Chemical]: 40 & 44kDa Immunofluorescence, Western Blotting
Compare Similar Items
Show Difference
Antigen: IGFBP-3
Classification: Monoclonal
Concentration: 250μg/mL
Description: IGF-Binding Protein-3
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 4
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human IGFBP-3 aa. 101-210
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Antigen:
IGFBP-3
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
IGF-Binding Protein-3
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
4
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human IGFBP-3 aa. 101-210
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Antigen: KIF3A
Classification: Monoclonal
Concentration: 250μg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 28
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human KIF3A aa. 563-671
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1
Antigen:
KIF3A
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
28
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human KIF3A aa. 563-671
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1
Antigen: DARPP-32
Classification: Monoclonal
Concentration: 250μg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 15
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human DARPP-32 aa. 70-181
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Mouse, Rat
Isotype: IgG1
Antigen:
DARPP-32
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
15
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human DARPP-32 aa. 70-181
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Mouse, Rat
Isotype:
IgG1
Antigen: Bid
Classification: Monoclonal
Concentration: 250μg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 7
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse Bid aa. 50-62
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Antigen:
Bid
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
7
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse Bid aa. 50-62
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1