MABD127MI
MilliporeSigma™ FBXO15, Mouse, Unlabeled, Clone: 3B11.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABD127MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABD127MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
FBXO15
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgMκ antibody in buffer containing PBS with 0.05% Sodium Azide.
Gene Accession No.
Q8NCQ5
Immunogen
KLH-conjugated linear peptide corresponding an N-terminal sequence of human FBXO15.
Quantity
200 μL
Research Discipline
Stem Cell Research
Gene ID (Entrez)
NP_001136430
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
3B11.1
Conjugate
Unconjugated
Gene
FBXO15, FBX15
Host Species
Mouse
Purification Method
Purified by Ion-Exchange Chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 3B11.1 recoginzes an N-terminal epitope present in spliced isoform 1 (UniProt Q8NCQ5-1), but absent in spliced isoform 2 (UniProt Q8NCQ5-2).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgM κ
Related Products
Description
- F-box only protein 15 (UniProt Q8NCQ5) is encoded by the FBXO15 (also known as FBX15) gene (Gene ID 201456) in human
- Polyubiquitination of proteins is mediated by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s)
- There exist RING finger-type, HECT-type, U-box-type, and PHD-finger-type E3 ligases
- The RING finger-type E3s include seven cullin-based E3s, such as SKP1–CUL1–F-box-protein (SCF) complex and the anaphase-promoting complex/cyclosome (APC/C)
- F-box proteins use their N-terminal F-box motif to bind Skp1 and other motif(s) in their C-terminal region for substrates recognition and recruitment
- F-box proteins are divided into the FBXW subclass that contains WD40 repeat domains, the FBXL subclass that contains leucine-rich repeat domains, and the F-box only (FBXO) subclass that contains not yet fully characterized substrate recognition domains
- SCF-Fbxo15 is reported to mediate the ubiquitination of cardiolipin synthase (CLS1) for proteasomal degradation in human lung epithelial cells
- PTEN-induced putative kinase 1 (PINK1) is shown to phosphorylate CLS1 and cause its release from the inner mitochondrial membrane to the outer membrane, making it accessible for Fbxo15-targeted ubiquitination.
Compare Similar Items
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Antigen: FBXO15
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgMκ antibody in buffer containing PBS with 0.05% Sodium Azide.
Gene Accession No.: Q8NCQ5
Immunogen: KLH-conjugated linear peptide corresponding an N-terminal sequence of human FBXO15.
Quantity: 200 μL
Research Discipline: Stem Cell Research
Gene ID (Entrez): NP_001136430
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 3B11.1
Conjugate: Unconjugated
Gene: FBXO15, FBX15
Host Species: Mouse
Purification Method: Purified by Ion-Exchange Chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 3B11.1 recoginzes an N-terminal epitope present in spliced isoform 1 (UniProt Q8NCQ5-1), but absent in spliced isoform 2 (UniProt Q8NCQ5-2).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgM κ
Antigen:
FBXO15
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgMκ antibody in buffer containing PBS with 0.05% Sodium Azide.
Gene Accession No.:
Q8NCQ5
Immunogen:
KLH-conjugated linear peptide corresponding an N-terminal sequence of human FBXO15.
Quantity:
200 μL
Research Discipline:
Stem Cell Research
Gene ID (Entrez):
NP_001136430
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
3B11.1
Conjugate:
Unconjugated
Gene:
FBXO15, FBX15
Host Species:
Mouse
Purification Method:
Purified by Ion-Exchange Chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 3B11.1 recoginzes an N-terminal epitope present in spliced isoform 1 (UniProt Q8NCQ5-1), but absent in spliced isoform 2 (UniProt Q8NCQ5-2).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgM κ
Antigen: PRDM1
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.: __
Immunogen: Purified recombinant fragment of human PRDM1 expressed in E. Coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Ascites
Applications: Western Blot
Clone: 5E7
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Antigen:
PRDM1
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.:
__
Immunogen:
Purified recombinant fragment of human PRDM1 expressed in E. Coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Ascites
Applications:
Western Blot
Clone:
5E7
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Antigen: ISL-1
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.: __
Immunogen: Purified recombinant fragment of human ISL1 expressed in E. Coli. corresponding to human ISL1.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Ascites
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Clone: 1H9
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Antigen:
ISL-1
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.:
__
Immunogen:
Purified recombinant fragment of human ISL1 expressed in E. Coli. corresponding to human ISL1.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Ascites
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
1H9
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Antigen: Wnt-5a
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.: __
Immunogen: Purified recombinant fragment of human Wnt-5a expressed in E. Coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Rat
Form: Ascites
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Clone: 6F2
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1
Antigen:
Wnt-5a
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.:
__
Immunogen:
Purified recombinant fragment of human Wnt-5a expressed in E. Coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Rat
Form:
Ascites
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
6F2
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1