MABF841
MilliporeSigma™ Mouse anti-FCGR2A/C, Clone: 11B6,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF841-Each-of-1 | In Stock | ₹ 36,571.77 |
MABF841 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,571.77
GST (18%): ₹ 6,582.919
Total Price: ₹ 43,154.689
Antigen
FCGR2A/C
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
CD32; FCG2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; IGFR2
Immunogen
Linear peptide corresponding to a cytoplasmic domain sequence identical in human FcγRIIa and FcγRIIc.
Quantity
100 μg
Research Discipline
Inflammation and Immunology
Gene ID (Entrez)
NP_001129691.1; NP_963857.3
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
11B6
Gene Accession No.
P12318; P31995
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects FCGR2A/C clone: 11B6 in Human samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blotting FcγRI/CD64, FcγRII/CD32, FcγRIII/CD16, and FcγRIV/CD16-2 represent the four known classes of IgG Fc receptors (FcγRs)
- FcγRII, FcγRIII, and FcγRIV are low-affinity receptors for monomeric IgG, whereas FcγRI is the only high-affinity FcγR
- FcγRs play important roles in inflammatory cell activation, clearance, presentation of Ag, and maintenance of IgG homeostasis
- In addition to binding immune complex (IC), FcγRs have been shown to bind non-IgG ligands
- For example, FcγRII is shown to bind oxLDL, while FcγRIII binding to an E
- coli component is reported to negatively regulate the function of macrophage receptor with collagenous structure (MARCO)
- FcyRII activation is also reported to transduce a negative regulatory signal against CD38 cross-linking-induced proliferation of resting mature B cells
- Low affinity immunoglobulin gamma Fc region receptor II-a/b/c (IgG Fc receptor II-a/-b/-c, CDw32, Fc-gamma RII-a/-b/-c, Fc-gamma-RIIa/b/c, FcRII-a/-b/-c, CD32) are encoded by the FCGR2A/B/C (CD32, FCG2, IGFR2) genes in human (UniProt P12318, P31994, P31995; Gene ID 2212, 2213, 9103)
- The FcγRIIs encoded by the three genes are highly conserved in their extracellular portion, with significant variation in the transmembrane and intracellular regions
- All three types of transcripts alternative splicing to generate additional isoforms.
Compare Similar Items
Show Difference
Antigen: FCGR2A/C
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CD32; FCG2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; IGFR2
Immunogen: Linear peptide corresponding to a cytoplasmic domain sequence identical in human FcγRIIa and FcγRIIc.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_001129691.1; NP_963857.3
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 11B6
Gene Accession No.: P12318; P31995
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
FCGR2A/C
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CD32; FCG2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; IGFR2
Immunogen:
Linear peptide corresponding to a cytoplasmic domain sequence identical in human FcγRIIa and FcγRIIc.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_001129691.1; NP_963857.3
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
11B6
Gene Accession No.:
P12318; P31995
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: __
Classification: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Antigen: EBI3 (Neutralizing)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ in buffer containing PBS without preservatives.
Gene Symbols: Ebi3; Il27b
Immunogen: Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_056581
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG2b κ
Applications: Neutralization, Western Blot
Clone: V1.4C4.22
Gene Accession No.: O35228
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
EBI3 (Neutralizing)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ in buffer containing PBS without preservatives.
Gene Symbols:
Ebi3; Il27b
Immunogen:
Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_056581
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG2b κ
Applications:
Neutralization, Western Blot
Clone:
V1.4C4.22
Gene Accession No.:
O35228
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: IDO-1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Ido1, Ido, Indo
Immunogen: KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.
Quantity: 100 μg
Research Discipline: Inflammation, Immunology
Gene ID (Entrez): NP_032350
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 4B7
Gene Accession No.: P28776
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Rat
Form: Purified
Antigen:
IDO-1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Ido1, Ido, Indo
Immunogen:
KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.
Quantity:
100 μg
Research Discipline:
Inflammation, Immunology
Gene ID (Entrez):
NP_032350
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4B7
Gene Accession No.:
P28776
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Form:
Purified