MABS1293
MilliporeSigma™ ING5, Rat, Unlabeled, Clone: 7A11,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1293-Each-of-1 | In Stock | ₹ 40,197.80 |
MABS1293 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
ING5
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rat IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q8WYH8
Immunogen
GST-tagged recombinant human ING5 (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_115705
Target Species
Human
Form
Purified
Applications
Immunoprecipitation, Western Blot
Clone
7A11
Conjugate
Unconjugated
Gene
ING5
Host Species
Rat
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 7A11 detected shRNA-mediated ING5 downregulation in HEK293 cells (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2a κ
Related Products
Description
- Inhibitor of growth protein 5 (UniProt Q8WYH8; also known as p28ING5) is encoded by the ING5 gene (Gene ID 84289) in human
- ING5 is a member of the ING family of proteins known for their antiporliferation activity
- ING proteins bind to methylated core histones through their PHD motif (a.a
- 186-235 in ING5), and ING5 is known to target histone H3 on di- or trimethylated Lys4 (H3K4me2/3)
- ING5 associates with two histone acetylase (HAT) complexes, HBO1 and nucleosomal H3-specific MOZ/MORF, that interact with the MCM helicase and are essential for DNA replication during S phase
- ING5 deregulations are reported in various cancers and ING5 located chromosome region is deleted in oral squamous cell carcinoma and odontogenic tumors
- In addition, ING5 cytosolic localization is reported in some head and neck squamous cell carcinoma tumors and the cytosolic localization positively correlates with the progression of gastric cancer
- ING5 also pormotes p53-dependent gene transcription by enhancing p53 acetylation in a p300-dependent manner
- ING5 is shown to interact with p63 that mediates the self-renewal of epidermal stem cells, and ING5 knockdown causes differentiation of epidermal stem cells
- Similar to other ING proteins, ING5 possesses a PHD (plant homeodomain) type zinc finger, an NCR (novel conserved region), a LZL (leucine zipper like) finger, and two NLS (nuclear localization sequence) motifs.
Compare Similar Items
Show Difference
Antigen: ING5
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rat IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q8WYH8
Immunogen: GST-tagged recombinant human ING5 (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_115705
Target Species: Human
Form: Purified
Applications: Immunoprecipitation, Western Blot
Clone: 7A11
Conjugate: Unconjugated
Gene: ING5
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 7A11 detected shRNA-mediated ING5 downregulation in HEK293 cells (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
ING5
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rat IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q8WYH8
Immunogen:
GST-tagged recombinant human ING5 (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_115705
Target Species:
Human
Form:
Purified
Applications:
Immunoprecipitation, Western Blot
Clone:
7A11
Conjugate:
Unconjugated
Gene:
ING5
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 7A11 detected shRNA-mediated ING5 downregulation in HEK293 cells (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Antigen: PAR4
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2bλ antibody in PBS without preservatives.
Gene Accession No.: Q96RI0
Immunogen: MBP-conjugated recombinant human PAR4 N-terminal fragment including the propeptide sequence.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_003941
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Inhibition Assays, Western Blot
Clone: 5F10
Conjugate: Unconjugated
Gene: F2RL3, PAR4
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 5F10 recognizes a propeptide epitope near (N-terminal to) the thrombin-cleavage site and protects cell surface PAR4 against thrombin cleavage (Mumaw, M.M., et al. (2015). Thromb. Res. 135(6):1165-1171). Clone 5F10 recognizes prepro- and pro-, but not proteolytically activated, forms of human PAR4.
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Isotype: IgG2b λ
Antigen:
PAR4
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2bλ antibody in PBS without preservatives.
Gene Accession No.:
Q96RI0
Immunogen:
MBP-conjugated recombinant human PAR4 N-terminal fragment including the propeptide sequence.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003941
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Inhibition Assays, Western Blot
Clone:
5F10
Conjugate:
Unconjugated
Gene:
F2RL3, PAR4
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 5F10 recognizes a propeptide epitope near (N-terminal to) the thrombin-cleavage site and protects cell surface PAR4 against thrombin cleavage (Mumaw, M.M., et al. (2015). Thromb. Res. 135(6):1165-1171). Clone 5F10 recognizes prepro- and pro-, but not proteolytically activated, forms of human PAR4.
Content And Storage:
Stable for 1 year at -20°C from date of receipt.
Isotype:
IgG2b λ
Antigen: ATP Synthase subunit β
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: P06576
Immunogen: His-tagged recombinant protein corresponding to human ATP Synthase subunit β.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001677
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone: 11/21-7-A8
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Antigen:
ATP Synthase subunit β
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
P06576
Immunogen:
His-tagged recombinant protein corresponding to human ATP Synthase subunit β.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001677
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone:
11/21-7-A8
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ