MABT165MI
MilliporeSigma™ anti-p130cas/BCAR1 Clone: 2C1.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT165MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABT165MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
p130cas/BCAR1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P56945
Host Species
Mouse
Purification Method
Purified by ion-exchange chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with all eight spliced isoforms of human p130Cas reported by UniProt (P56945-1 through P56945-8).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgM κ
Applications
Western Blot
Clone
2C1.1
Formulation
Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.
Gene Symbols
BCAR1, CAS, CAS1, CASS1, CRKAS
Immunogen
GST-tagged recombinant human p130cas/BCAR1 C-terminal fragment.
Quantity
100 μL
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_055382
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects p130cas/BCAR1 Clone: 2C1.1 in Human samples, and it is validated for Western Blotting Breast cancer anti-estrogen resistance protein 1 (UniProt P56945; also known as Cas scaffolding protein family member 1, Crk-associated substrate, p130Cas) is encoded by the BCAR1 (also known as CAS, CAS1, CASS1, CRKAS) gene (Gene ID 9564) in human
- p130Cas/BCAR1 is an adaptor protein that belongs to the CAS family of scaffold proteins, members of which also include Nedd9, HEF-1 (CAs-L), EFS, and CASS4
- Structurally, p130Cas is composed of a Src-homology 3 (SH3) domain, an adjacent large substrate-binding domain containing 15 repetitions of the YxxP motif, a main site of tyrosine phosphorylation on the p130Cas/BCAR1 molecule that generates SH2-binding sites, a proline and serine rich region, and a highly conserved four-helix bundle (focal adhesion targeting [FAT] domain)
- p130Cas/BCAR1 plays an important role in transducing signaling originated from mechanical stimuli, extracellular matrix (ECM) adhesion, as well as growth factor stimulation cascades during normal development and diseases.
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Antigen: p130cas/BCAR1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P56945
Host Species: Mouse
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with all eight spliced isoforms of human p130Cas reported by UniProt (P56945-1 through P56945-8).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgM κ
Applications: Western Blot
Clone: 2C1.1
Formulation: Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.
Gene Symbols: BCAR1, CAS, CAS1, CASS1, CRKAS
Immunogen: GST-tagged recombinant human p130cas/BCAR1 C-terminal fragment.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_055382
Target Species: Human
Form: Purified
Antigen:
p130cas/BCAR1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P56945
Host Species:
Mouse
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with all eight spliced isoforms of human p130Cas reported by UniProt (P56945-1 through P56945-8).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgM κ
Applications:
Western Blot
Clone:
2C1.1
Formulation:
Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.
Gene Symbols:
BCAR1, CAS, CAS1, CASS1, CRKAS
Immunogen:
GST-tagged recombinant human p130cas/BCAR1 C-terminal fragment.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_055382
Target Species:
Human
Form:
Purified
Antigen: Transgelin/SM22a
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_001001522
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunocytochemistry, Western Blot
Clone: 20F2.2
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: TAGLN, SM22, WS3-10
Immunogen: GST-tagged recombinant protein corresponding to human Transgelin/SM22a.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
Transgelin/SM22a
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_001001522
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Western Blot
Clone:
20F2.2
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
TAGLN, SM22, WS3-10
Immunogen:
GST-tagged recombinant protein corresponding to human Transgelin/SM22a.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: MMP-9 (Active)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_004985
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunohistochemistry, Western Blot
Clone: 4A3
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: MMP9, CLG4B
Immunogen: Ovalbumin-conjugated linear peptide corresponding to the N-terminus of human MMP-9 (Active).
Quantity: 200 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Antigen:
MMP-9 (Active)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_004985
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Western Blot
Clone:
4A3
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
MMP9, CLG4B
Immunogen:
Ovalbumin-conjugated linear peptide corresponding to the N-terminus of human MMP-9 (Active).
Quantity:
200 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Antigen: Syndecan-1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P18827
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 11G2.1 recognizes an extracellular epitope.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Western Blot
Clone: 11G2.1
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human Syndecan-1 extracellular domain fragment.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001006947
Target Species: Human
Form: Purified
Antigen:
Syndecan-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P18827
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 11G2.1 recognizes an extracellular epitope.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
11G2.1
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human Syndecan-1 extracellular domain fragment.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001006947
Target Species:
Human
Form:
Purified