MABS522MI
MilliporeSigma™ anti-PIKFYVE Clone: R159.4.3C9,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS522MI-Each-of-1 | In Stock | ₹ 39,063.27 |
MABS522MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,063.27
GST (18%): ₹ 7,031.389
Total Price: ₹ 46,094.659
Antigen
PIKFYVE
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
Q9Y2I7
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with all four spliced isoforms of human PIKfyve reported by UniProt (Q9Y2I7-1 through Q9Y2I7-4).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2a κ
Applications
Western Blot
Clone
R159.4.3C9
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
PIKFYVE, CFD, FAB1, HEL37, KIAA0981, PIP5K, PIP5K3, ZFYVE29
Immunogen
AviTag-6xHis-tagged recombinant protein corresponding an internal fragment of human PIKFYVE.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_055855
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects PIKFYVE Clone: R159.4.3C9 in Human samples, and it is validated for Western Blotting 1-phosphatidylinositol 3-phosphate 5-kinase (EC 2.7.1.150; UniProt Q9Y2I7; also known as Epididymis luminal protein 37, FYVE finger-containing phosphoinositide kinase, PIKfyve, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type III PIP kinase, Zinc finger FYVE domain containing 29) is encoded by the PIKFYVE (also known as CFD, FAB1, HEL37, KIAA0981, PIP5K, PIP5K3, ZFYVE29) gene (Gene ID 200576) in human
- PIKfyve is a class III lipid kinase that is responsible for phosphorylating phosphatidylinositol (PtdIns) and phosphatidylinositol 3-phosphate (PtdIns3P) of their inositol ring at the D-5 position to form PtdIns3P and PtdIns(3,5)P2 (phosphatidylinositol 3,5-bisphosphate), respectively
- PIKfyve forms a stable ternary heterooligomeric complex with its regulator ArPIKfyve (encoded by the VAC14 gene) and the Sac1 domain-containing PtdIns(3,5)P2 5-phosphatase Sac3 (encoded by the FIG4 gene), and both ArPIKfyve and Sac3 are required for maximal PIKfyve activity
- PIKfyve is also known to interact with the Rab9 effector RABEPK and the kinesin adaptor JLP (encoded by SPAG9)
- By regulating endosomal trafficking, PIKfyve plays an important role in multiple biological processes, such as GLUT4 translocation, retroviral budding, autophagy, and neurodegeneration
- Human PIKfyve is initially produced as a 2098-amino acid protein whose N-terminal initiator methionine is removed posttranslationally
- PIKFYVE gene mutation is linked to corneal fleck dystrophy (CFD) characterized by white flecks scattered in all levels of the stroma.
Compare Similar Items
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Antigen: PIKFYVE
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9Y2I7
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with all four spliced isoforms of human PIKfyve reported by UniProt (Q9Y2I7-1 through Q9Y2I7-4).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2a κ
Applications: Western Blot
Clone: R159.4.3C9
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PIKFYVE, CFD, FAB1, HEL37, KIAA0981, PIP5K, PIP5K3, ZFYVE29
Immunogen: AviTag-6xHis-tagged recombinant protein corresponding an internal fragment of human PIKFYVE.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_055855
Target Species: Human
Form: Purified
Antigen:
PIKFYVE
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9Y2I7
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with all four spliced isoforms of human PIKfyve reported by UniProt (Q9Y2I7-1 through Q9Y2I7-4).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
R159.4.3C9
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PIKFYVE, CFD, FAB1, HEL37, KIAA0981, PIP5K, PIP5K3, ZFYVE29
Immunogen:
AviTag-6xHis-tagged recombinant protein corresponding an internal fragment of human PIKFYVE.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_055855
Target Species:
Human
Form:
Purified
Antigen: HGPRT
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P00492
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 13H11.1
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: HPRT1; HPRT
Immunogen: GST-tagged human HGPRT recombinant fragment lacking N- and C-terminal regions.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000185
Target Species: Human
Form: Purified
Antigen:
HGPRT
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P00492
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
13H11.1
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
HPRT1; HPRT
Immunogen:
GST-tagged human HGPRT recombinant fragment lacking N- and C-terminal regions.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000185
Target Species:
Human
Form:
Purified
Antigen: MEKK5
Classification: Monoclonal
Conjugate: __
Gene Accession No.: O35099
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: TC003
Formulation: Purified rat monoclonal IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Map3k5; Ask1; Mekk5
Immunogen: Recombinant protein corresponding to the C-terminus of mouse MEKK5.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_032606
Target Species: Mouse
Form: Purified
Antigen:
MEKK5
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
O35099
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
TC003
Formulation:
Purified rat monoclonal IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Map3k5; Ask1; Mekk5
Immunogen:
Recombinant protein corresponding to the C-terminus of mouse MEKK5.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_032606
Target Species:
Mouse
Form:
Purified
Antigen: GREB1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_055483
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: GREB1Ab
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: GREB1
Immunogen: Recombinant protein corresponding to human GREB1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Antigen:
GREB1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_055483
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
GREB1Ab
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
GREB1
Immunogen:
Recombinant protein corresponding to human GREB1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified