MABS1288

MilliporeSigma™ VLDLR, Rat, Unlabeled, Clone: 4C4G5,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1288-Each-of-1 In Stock ₹ 40,197.80

MABS1288 - Each of 1

₹ 40,197.80

In Stock

Quantity

1

Base Price: ₹ 40,197.80

GST (18%): ₹ 7,235.604

Total Price: ₹ 47,433.404

Antigen

VLDLR

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rat IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P98156

Immunogen

GST-tagged recombinant mouse VLDLR cytoplasmic tail (Hirota, Y., et al. (2015). J. Comp. Neurol. 523(3):463-478).

Quantity

100 μL

Research Discipline

Signaling

Gene ID (Entrez)

NP_001154892

Target Species

Mouse

Form

Purified

Applications

Western Blot

Clone

4C4G5

Conjugate

Unconjugated

Gene

Vldlr

Host Species

Rat

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 4C4G5 (4G) detected VLDLR expression in embryonic and neonatal brain tissues from wild-type, but not Vldlr-knockout mice (Hirota, Y., et al. (2015). J. Comp. Neurol. 523(3):463-478).

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG2b κ

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Description

  • Pulmonary surfactant-associated protein D (UniProt P35247; also known as Collectin-7, Lung surfactant protein D, PSP-D, SP-D) is encoded by the SFTPD (also known as COLEC7, PSPD, SFTP4) gene (Gene ID 6441) in human
  • Surfactant, produced by alveolar type II cells and airway Clara cells, resides at the air-liquid interface of the lungs and is most commonly known for its role in reducing surface tension
  • Surfactant is a lipoprotein complex composed of approximately 10% proteins, including surfactant protein A (SP-A), SP-B, SP-C, and SP-D
  • SP-A and SP-D belong to the collectin family of proteins and can modulate innate immunity
  • SP-D is known to enhance pulmonary clearance of pathogens, such as Pseudomonous aerginosa, Klebsiella pneumonia, respiratory syncytial virus (RSV) and Influenza virus
  • SP-D is also shown to modify allergic responsee in the lungs by binding common allergens, including house dust mite and pollen particles
  • SP-A-deficient and SP-D-deficient mice are susceptible to bleomycin-induced lung injury and display increased cellular inflammation, more severe lung fibrosis, and reduced survival
  • In addition to lung, SP-D is also reported to be detected in extrapulmonary tissues, such as kidney and pancreas
  • Serum levels of either SP-A or SP-D in human are correlated with mortality in patients with pulmonary fibrosis
  • Human SP-D is produced with a signal peptide sequence (a.a
  • 1-20), which is removed posttranslationally to yield the mature protein (a.a
  • 21-375) that contains a collagen-like domain (a.a
  • 46-222), a coiled coil region (a.a
  • 223-252), and a C-type lectin domain (a.a
  • 260-375).

Compare Similar Items

Show Difference

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MilliporeSigma™

MABS1288

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Antigen:
VLDLR

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rat IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P98156

Immunogen:
GST-tagged recombinant mouse VLDLR cytoplasmic tail (Hirota, Y., et al. (2015). J. Comp. Neurol. 523(3):463-478).

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001154892

Target Species:
Mouse

Form:
Purified

Applications:
Western Blot

Clone:
4C4G5

Conjugate:
Unconjugated

Gene:
Vldlr

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 4C4G5 (4G) detected VLDLR expression in embryonic and neonatal brain tissues from wild-type, but not Vldlr-knockout mice (Hirota, Y., et al. (2015). J. Comp. Neurol. 523(3):463-478).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2b κ

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MilliporeSigma™

MABS1289MI

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Antigen:
T4 Lysozyme (T4L)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P00720

Immunogen:
Recombinant T4L fusion protein.

Quantity:
100 μg

Research Discipline:
Epitope Tags & General Use

Gene ID (Entrez):
NP_049736.1

Target Species:
All species

Form:
Purified

Applications:
Western Blot

Clone:
6A6

Conjugate:
Unconjugated

Gene:
Bacteriophage T4 gene E

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 6A6 detects T4L and recombinant T4L fusion proteins.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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MABS1290MI

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Antigen:
LANCL2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
GST-tagged full length human recombinant LANCL2 protein.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_061167

Target Species:
Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
392

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein A Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 392 detected LANCL2 overexpressed in HEK293 cells.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

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MABS1293

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Antigen:
ING5

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rat IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q8WYH8

Immunogen:
GST-tagged recombinant human ING5 (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_115705

Target Species:
Human

Form:
Purified

Applications:
Immunoprecipitation, Western Blot

Clone:
7A11

Conjugate:
Unconjugated

Gene:
ING5

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 7A11 detected shRNA-mediated ING5 downregulation in HEK293 cells (Linzen, U., et al. (2015). PLoS One. 10(4):e0123736).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ