MABT826MI

MilliporeSigma™ anti-Actin Clone: 2G2,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABT826MI-Each-of-1 In Stock ₹ 40,197.80

MABT826MI - Each of 1

₹ 40,197.80

In Stock

Quantity

1

Base Price: ₹ 40,197.80

GST (18%): ₹ 7,235.604

Total Price: ₹ 47,433.404

Antigen

Actin

Classification

Monoclonal

Conjugate

Unconjugated

Gene Accession No.

P68135

Host Species

Mouse

Purification Method

Purified by ion-exchange chromatography

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Chicken, Frog, Human, Monkey, Mouse, Rabbit, Rat

Form

Purified

Applications

Immunocytochemistry, Western Blot

Clone

2G2

Formulation

Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.

Gene Symbols

ACTA1, ACTA

Immunogen

Reconstituted complex of rabbit skeletal muscle actin and calf thymus profilin.

Quantity

100 μL

Research Discipline

Cell Structure

Test Specificity

Clone 2G2 recognizes a tripartite epitope identified in a region of the actin monomer (G-actin) that is not exposed on the surface the filamentous F-actin, but is accessible on the surface of profilin-complexed actin molecule (Gonsior, S.M., et al. (1999). J. Cell Sci. 112 (Pt 6):797-809).

Content And Storage

2°C to 8°C for one year from date of shipment

Isotype

IgM κ

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Description

  • Specifically detects Actin Clone: 2G2 in Chicken, Frog, Human, Monkey, Mouse, Rabbit, Rat samples, and it is validated for Immunocytochemistry, Western Blotting Actin, alpha skeletal muscle (UniProt P68135; also known as Alpha-actin-1) is encoded by the ACTA1 (also known as ACTA) gene (Gene ID 100009506) in Oryctolagus cuniculus (Rabbit) species
  • Actins exist in a variety of structural states, depending on the specific ionic conditions or the interaction with ligand proteins
  • The oligomeric and polymeric forms that actin molecules assume are dependent on the distinct conformations they adopt
  • Research indicates distinct actin conformations/structures in the nucleus and the cytoplasm of different cell types and that their distribution varies in response to external signals
  • In additon to serving as the basic building blocks of cytoskeletal microfilaments, actins are involved in multiple nuclear functions and adopt specific conformations that are important for their association with nuclear actin-binding proteins.

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Img

MilliporeSigma™

MABT826MI

--


Antigen:
Actin

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P68135

Host Species:
Mouse

Purification Method:
Purified by ion-exchange chromatography

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Chicken, Frog, Human, Monkey, Mouse, Rabbit, Rat

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
2G2

Formulation:
Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.

Gene Symbols:
ACTA1, ACTA

Immunogen:
Reconstituted complex of rabbit skeletal muscle actin and calf thymus profilin.

Quantity:
100 μL

Research Discipline:
Cell Structure

Test Specificity:
Clone 2G2 recognizes a tripartite epitope identified in a region of the actin monomer (G-actin) that is not exposed on the surface the filamentous F-actin, but is accessible on the surface of profilin-complexed actin molecule (Gonsior, S.M., et al. (1999). J. Cell Sci. 112 (Pt 6):797-809).

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgM κ

Img

MilliporeSigma™

MABT827AF48

--


Antigen:
Dystrophin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Accession No.:
P11532

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
__

Applications:
Immunofluorescence

Clone:
2C6 (MANDYS106)

Formulation:
Purified mouse IgG2a Alexa Fluor™ 488 conjugate in buffer containing PBS, 1.5% BSA with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
TrpE-tagged recombinant protein corresponding to the Exon 43-coded pectrin-like repeat 16 region of human Dystrophin.

Quantity:
100 μL

Research Discipline:
Cell Structure

Test Specificity:
Detects dystrophin spliced isoforms 1-4, but not isoforms 5-10, or utrophin. Positive muscle membrane staining of tissue samples from healthy donors, reduced staining of Becker muscular dystrophy (BMD) biopsies, and no staining is seen with Duchenne muscular dystrophy (DMD) biopsy samples (Anthony, K., et al. (2011). Brain. 134(Pt 12):3547-3559).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

Img

MilliporeSigma™

MABT827AF55

--


Antigen:
Dystrophin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 555

Gene Accession No.:
P11532

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
__

Applications:
Immunofluorescence

Clone:
2C6 (MANDYS106)

Formulation:
Purified mouse IgG2a Alexa Fluor™ 555 conjugate in buffer containing PBS, 1.5% BSA with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
TrpE-tagged recombinant protein corresponding to the Exon 43-coded pectrin-like repeat 16 region of human Dystrophin.

Quantity:
100 μL

Research Discipline:
Cell Structure

Test Specificity:
Detects dystrophin spliced isoforms 1-4, but not isoforms 5-10, or utrophin. Positive muscle membrane staining of tissue samples from healthy donors, reduced staining of Becker muscular dystrophy (BMD) biopsies, and no staining is seen with Duchenne muscular dystrophy (DMD) biopsy samples (Anthony, K., et al. (2011). Brain. 134(Pt 12):3547-3559).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

Img

MilliporeSigma™

MABT827MI

--


Antigen:
Dystrophin

Classification:
Monoclonal

Conjugate:
__

Gene Accession No.:
P11532-1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
2C6 (MANDYS106)

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
DMD

Immunogen:
TrpE-tagged recombinant protein corresponding to the Exon 43-coded pectrin-like repeat 16 region of human Dystrophin.

Quantity:
100 μL

Research Discipline:
Cell Structure

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ