MABN1814MI
MilliporeSigma™ Neurogenin-2, Mouse, Unlabeled, Clone: 7G4,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN1814MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABN1814MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Neurogenin-2
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P70447
Immunogen
GST-tagged mouse neurogenin-2 N-terminal fragment (Lo, L., et al. (2002). Development. 129(7):1553-1567).
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_033848
Target Species
Mouse
Form
Purified
Applications
Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
7G4
Conjugate
Unconjugated
Gene
Neurog2, Ath4a, Atoh4, Ngn2
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
The specific staining by clone 7G4 was blocked by NGN2-GST fusion, but not by NGN1-fusion protein (Lo, L., et al. (2002). Development. 129(7):1553-1567).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2a κ
Related Products
Description
- Neurogenin-2 (UniProt P70447; also known as Helix-loop-helix protein mATH-4A, mATH4A, NGN-2, Protein atonal homolog 4) is encoded by the Neurog2 (also known as Ath4a, Atoh4, Ngn2) gene (Gene ID 11924) in murine species
- Neuronal differentiation is largely under the control of basic Helix-Loop-Helix (bHLH) proneural transcription factors that play key roles during development of the embryonic nervous system
- Neurogenin-2 (NGN-2) is a bHLH proneural transcription factor that orchestrates the progression from neural progenitor to differentiating neuron in several regions of the central nervous system, including the formation of sensory neurons from the epibranchial placode and neurogenesis in dorsal root ganglia
- NGN-2 dimerizes with TCF3 (E12/E47), the heterodimer then binds to target DNA regions and recruit transcriptional coactivators, such as p300/CBP and Brg1, to facilitate the transcription of a cascade of additional bHLH transcription factors, such as NeuroD, as well as structural and functional genes associated with mature neuronal activity.
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Antigen: Neurogenin-2
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P70447
Immunogen: GST-tagged mouse neurogenin-2 N-terminal fragment (Lo, L., et al. (2002). Development. 129(7):1553-1567).
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_033848
Target Species: Mouse
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 7G4
Conjugate: Unconjugated
Gene: Neurog2, Ath4a, Atoh4, Ngn2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The specific staining by clone 7G4 was blocked by NGN2-GST fusion, but not by NGN1-fusion protein (Lo, L., et al. (2002). Development. 129(7):1553-1567).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Neurogenin-2
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P70447
Immunogen:
GST-tagged mouse neurogenin-2 N-terminal fragment (Lo, L., et al. (2002). Development. 129(7):1553-1567).
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_033848
Target Species:
Mouse
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
7G4
Conjugate:
Unconjugated
Gene:
Neurog2, Ath4a, Atoh4, Ngn2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The specific staining by clone 7G4 was blocked by NGN2-GST fusion, but not by NGN1-fusion protein (Lo, L., et al. (2002). Development. 129(7):1553-1567).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: α-Synuclein
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P37840
Immunogen: Purified human erythrocyte α-synuclein.
Quantity: 100 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000336
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 2F12
Conjugate: Unconjugated
Gene: SNCA, NACP, PARK1, PARK4
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 2F12 reacted with both monomeric and aggregated forms of alpha-synuclein of human, mouse, and rat species. Clone 2F12 detected both wild-type alpha-synuclein and fPD mutants (Dettmer, U., et al. (2015). Nat. Commun. 6:7314; Dettmer, U., et al. (2013). J. Biol. Chem. 288(9):6371-6385).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
α-Synuclein
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P37840
Immunogen:
Purified human erythrocyte α-synuclein.
Quantity:
100 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000336
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
2F12
Conjugate:
Unconjugated
Gene:
SNCA, NACP, PARK1, PARK4
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 2F12 reacted with both monomeric and aggregated forms of alpha-synuclein of human, mouse, and rat species. Clone 2F12 detected both wild-type alpha-synuclein and fPD mutants (Dettmer, U., et al. (2015). Nat. Commun. 6:7314; Dettmer, U., et al. (2013). J. Biol. Chem. 288(9):6371-6385).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: α-Synuclein
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P37840
Immunogen: Purified human erythrocyte alpha-synuclein.
Quantity: 200 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000336
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: SOY1
Conjugate: Unconjugated
Gene: SNCA, NACP, PARK1, PAR
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone SOY1 detected both wild-type alpha-synuclein and fPD mutants (Dettmer, U., et al. (2015). Nat. Commun. 6:7314). Clone SOY1 targets a C-terminal half epitope present in all three human spliced iisoforms, NACP140, NACP112, and NACP126, reported by UniProt (P37840). Clone SOY1 also exhibits murine cross-reactivity, albeit at a lower sensitivity than that of human alpha-synuclein.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
α-Synuclein
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P37840
Immunogen:
Purified human erythrocyte alpha-synuclein.
Quantity:
200 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000336
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
SOY1
Conjugate:
Unconjugated
Gene:
SNCA, NACP, PARK1, PAR
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone SOY1 detected both wild-type alpha-synuclein and fPD mutants (Dettmer, U., et al. (2015). Nat. Commun. 6:7314). Clone SOY1 targets a C-terminal half epitope present in all three human spliced iisoforms, NACP140, NACP112, and NACP126, reported by UniProt (P37840). Clone SOY1 also exhibits murine cross-reactivity, albeit at a lower sensitivity than that of human alpha-synuclein.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: Atlastin-1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q8WXF7
Immunogen: Linear peptide corresponding to the N-terminal sequence of human Atlastin-1.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_056999
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 3194
Conjugate: Unconjugated
Gene: ATL1, GBP3, HSN1D, SPG3, SPG3A
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 3194 targets an N-terminal epitope present in both spliced isoforms of human Atlastin-1 reported by UniProt (Q8WXF7).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Atlastin-1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q8WXF7
Immunogen:
Linear peptide corresponding to the N-terminal sequence of human Atlastin-1.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_056999
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
3194
Conjugate:
Unconjugated
Gene:
ATL1, GBP3, HSN1D, SPG3, SPG3A
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 3194 targets an N-terminal epitope present in both spliced isoforms of human Atlastin-1 reported by UniProt (Q8WXF7).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ